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纤溶酶原激活物抑制剂-1与代谢综合征的相关性 被引量:2

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摘要 目的研究代谢综合征(MS)与血浆纤溶酶原激活物抑制剂-1(PAI-1)的相关性。方法所有试验资料和数据皆取自我市獐子岛流行病学调查资料,参与流调者共1 027人,其中按照国际糖尿病联盟(IDF)关于MS的诊断标准,筛选出MS患者53例,再随机选取健康对照组75例,由专人记录并测定受试者的年龄、性别、身高、体重及血压等临床资料。采集受试者外周静脉血,测定血糖、血脂、血尿酸、空腹血胰岛素、PAI-1水平,采集尿液测定尿微量白蛋白和尿肌酐。结果 MS患者血浆中PAI-1的水平较对照组升高(P<0.01)。结论 PAI-1活性升高是MS患者的特征之一,血胰岛素水平升高与PAI-1升高有关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第14期2645-2646,共2页 Chinese Journal of Gerontology
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参考文献9

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