肝移植术后早期不同营养方式对感染率的影响

Influence of different methods of nutritional support on infection rate during the early postoperative period of liver transplantation

目的探讨肝移植术后早期不同营养方式对感染率的影响。方法选择肝移植术后早期(移植后1～7 d)进行营养支持治疗的受者45例,随机分成3组,即肠外营养支持(PN)组、肠内营养支持(EN)组、代谢调理(MI)组(肠内营养支持+谷氨酰胺及精氨酸静脉注射),每组15例。各组营养支持均为等热量和等氮量。观察各组受者术后2周感染率的发生情况。结果 EN组和MI组术后2周感染率显著低于PN组(P<0.05),EN组和MI组比较无统计学差异(P>0.05)。结论在肝移植术后早期营养支持治疗中,肠内营养和代谢调理营养较之肠外营养更能有效地降低术后感染率。

Objective To investigate the influence of different methods of nutritional support on infection rate during the early postoperative period of liver transplantation（LTx）.Methods Forty-five LTx recipients,who were to be given nutritional support in the early postoperative stage（1-7 days after operation）,were randomly assigned into parental nutrition（PN） group,enteral nutrition（EN） group and metabolic intervention（MI） group（EN＋glutamine＋arginine） with 15 cases in each group.Each group of nutritional support received equal amounts of nitrogen and calories.The infection rate of each group in 2 weeks post-LTx was observed.Results The infection rate within 2 weeks post-LTx between the EN and MI group showed no difference,but both was significantly lower than that of the PN group（P0.05）.Conclusions EN and MI supports are more effective than PN support in reducing the risk of infection during the early postoperative period of LTx.