前列腺解剖带区的断层切片与MRI图像对照研究

Comparative study of the sectional slice of the prostate zone with its MRI images

目的探讨前列腺各带区在解剖断层切片的形态学表现,及其与MRI断层图像的对应关系,确定前列腺各带区MRI影像的解剖学基础。方法利用MRI技术对6具成人尸体及576例健康成人的前列腺进行扫描,观察尸体及活体前列腺带区MRI表现,然后采用火棉胶包埋技术把标本制成前列腺区薄层连续切片,并与MRI图片进行对照研究。结果尸体断层解剖切片可根据尿道、精阜、射精管识别外周带、中央带、移行带、尿道周围组织及前列腺肌肉基质区的大体位置,但其间未见明显界限。尸体标本及活体MRI图像表现基本一致,即T1WI上整个前列腺呈略低信号;T2WI上前列腺外周带呈高信号表现,中央区呈低信号;薄层切片与MRI图像有良好的对应关系。结论 MRI检查时,横断面、冠状面及矢状面扫描相结合,才能完整显示前列腺各带区的结构特点,进而有利于对前列腺内的病灶进行准确地MRI定位诊断。

Objective To compare morphological features of the prostate zones with its corresponding MRI images, and provide anatomical basis for MRI diagnosis of prostate zone diseases. Methods Prostate area of 576 normal persons and 6 cadaveric specimens were performed MRI scan and image analysis. And then, series sections of cadaveric prostate zone were prepared by using celloidin embedding method, for the comparative studying of MRI images and morphologic features. Results On the sectional specimens, periphery zone, central zone, transitional zone, paraurethral gland zone and fibrous muscle zone of prostate can be roughly identified according to the anatomic location of urethra, seminal crest and ejaculatory duct. On MRI images, outline of prostate presented clearly on T1WI condition, and periphery zone of prostate showed higher signal than that of central zone. The sectional data could be corresponded to MRI data completely. Conclusions To scan and analyze prostate zones through transversal, coronal and sagittal scan is helpful for accurate diagnosis and allocation of intraprostatic diseases.