韦氏智力量表检测肝硬化患者智力障碍的临床意义

The clinical significance of Wechsler Adult Intelligence Scale for assessment of mental abnormality in patient with liver cirrhosis

目的 探讨利用韦氏智力量表检测肝硬化患者智力障碍的临床意义. 方法 对49 例肝炎肝硬化患者采用韦氏智力量表进行了智商的检测,并与正常人的检测结果进行比较.结果 病例组的言语智商、操作智商及全智商都非常显著地低于对照组,在病例组内的操作智商也显著地低于言语智商。肝硬化患者言语及/ 或操作智商异常19 例(39 % ) , 操作智商异常率随肝功能损害严重程度而递增。结论 部分肝硬化患者存在智力障碍。

Objective To explore the clinical significance of Wechsler Adult Intelligence Scale for assessment of mental abnormality in patient with liver cirrhosis . Methods Wechsler Adult Intelligence Scale (WAIS) was performed in 49 patients with hepatic cirrhosis and the results were compared with matched healthy controls. Results All of the VIQ 、the PIQ and FIQ in patients were lower than healthy controls(P<0.01), and patients' PIQ < patients' VIQ(P<0.05). Verbal ability and/or performance tests were abnormal in 19 (39%) patients. The abnormal rate of performance test was increased with the severity of liver function impairment. Conclusions The patient with liver cirrhosis has mental abnormality,andthe abnormality rate of performance test increased with the severity of liver function impairment.