终末期肝病模型对肝硬化患者预后评估价值的研究进展

Progress of model for end-stage liver disease in the value of prognostic evaluation in patients with cirrhosis

客观、准确地判断肝硬化患者的病情及预后有助于指导临床医生选择正确的治疗方案。终末期肝病模型(MELD)是目前被广泛认可的评估终末期肝病严重程度的评分体系。近年来各种基于MELD评分发展而来的新评分系统不断涌现。加入新的变量例如血清钠可进一步提高MELD的预测能力,此文就MELD的研究现状作一综述。

An accurate, objective scoring system for severity and prognosis of liver disease is highly important for clinical management of patients with cirrhosis. The model for end-stage liver disease （MELD） score is a prospectively developed and validated scale for the severity of end-stage liver disease. Some new MELD-based prognostic models have been proposed in recent years. Incorporation of additional parameters, such as serum sodium level may further improve its prognostic accuracy. This article reviews the research state of prognostic models of end-stage liver disease.