PCR-SSP方法对西北地区回族NA抗原基因分型

Typing of NA Gene in the Hui Nationality in North west China by PCR SSP

目的:通过NA基因分型,了解中国西北地区回族人群NA基因多态性。方法:用PCR-SSP方法对115名健康、无血缘关系个体进行NA 基因分型。结果:在研究对象中NA1 基因频率为0.5696,NA2 基因频率为0.4304。结论:在我国西北地区回族中,NA杂合子多于纯合子,NA1

Objective:To understand the neutrophil antigen(NA) gene polymorphism in the Hui nationality in North west China by typing of NA gene.Method:The NA genes was typed by polymerase chain reation with sequence specific primers in the 115 healthy individuals without blood relationship.Results:The frequency of NA1 gene and NA2 gene was 0.5696 and 0.4304 in the objects studied,respectively.Conclusion:In the Hui nationality in North west China, there are more NA heterozygotes than NA homozygotes, and the frequency of NA1 gene is higher than that of NA2 gene.