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微阵列制备机器人分向前馈误差补偿控制

Two-way feed-forward error compensation control of a microarray production robot
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摘要 为了提高半闭环微阵列制备机器人的定位精度,根据机器人运动误差具有方向性的特点,提出了分向前馈误差补偿技术。建立了微阵列制备机器人系统误差前馈补偿的传递函数模型,对系统的准确性、快速性与稳定性进行分析,从理论上证明该方法在提高机器人精度方面是可行有效的。研究并实施了回程误差与其他非线性误差的分向补偿算法。在清华大学开发的THU-biorobot微阵列制备机器人上进行了实验研究。结果表明:补偿后机器人的定位精度在±5μm以内,系统动态性能也有显著提高,能够满足微阵列制备要求。 The positioning accuracy of a semi-closed control loop for a robot to produce microarrays was improved by a two-way feed-forward error compensation method based on the fact that the motion errors of the robot are directional.The motion control transfer function including the feed-forward compensation block was used to analyze the accuracy,speed and stability of the robotic system.This showed that error compensation method can significantly improve the accuracy.Two-way error compensation was then developed for the hysteresis error and other nonlinear errors.Tests on the THU-biorobot microarray production system demonstrated by Tsinghua University that the positioning error was reduced to less than ±5 μm,with the dynamic performance significantly improved by the error compensation method.
出处 《清华大学学报(自然科学版)》 EI CAS CSCD 北大核心 2011年第5期582-586,共5页 Journal of Tsinghua University(Science and Technology)
基金 国家“八六三”高技术项目(2009AA043701) 摩擦学国家重点实验室项目(SKLT09A03)
关键词 微阵列制备机器人 定位精度 分向补偿 前馈误差补偿 回程误差 microarray making robot positioning accuracy two-way error compensation forward error compensation hysteresis error
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参考文献14

  • 1Hanczar B, Hua J P, Sima C. Small-sample precision of ROC related estimates [J]. Bioinformatics, 2010, 26(6) : 822 -830.
  • 2Lee C Y, Lee Z J, Weng Y L. An improving gene selection for microarray dala [J]. 2009 IEEE international conference on fuzzy systems, 2009(3) : 1255 - 1258.
  • 3l.oris N, Alessandra L, Shery B. Advanced machine learning techniques for microarray spot quality classification [J]. Neural Comput &Applic, 2010(19) : 471 - 475.
  • 4Schena M. Microarray analysis [M].北京:科学出版社,2003.
  • 5Berlrand L, Asaph A, Schena M. Overview of DNA chip technology [J].Molecular Breeding, 1998(4) : 277 - 289.
  • 6魏庆娟,闫永楠,孔波,秦玉华.微阵列技术的应用及发展趋势[J].东北电力大学学报,2008,28(6):17-21. 被引量:4
  • 7Qiong S, Timothy N, l.an Y. Automated real time spotting system for DNA/protein microarray applications [J]. IEEE Transactions on Industrial Electronics, 2008, 55(9) : 120-123.
  • 8William F, Zhang M J. A biochip microarray fabrication system using inkier technology [J]. IEEE gransactionson automation science and engineering, 2007, 4(4) : 488 - 500.
  • 9Eugene B, Liao H L, Tuong C, et al. Integrated approaches for the identification of human hepatocyte nuclear factor 4 target genes using protein binding microarrays [J]. Hepatology, 2010, 5(2): 642- 653.
  • 10Timothy C, Suganya P, Tong W, et al. Automated liquid dispensing pin for microarray applications [J]. IEEE transactions on automation science and engineering, 2006, 3(2) : 187 - 191.

二级参考文献32

  • 1谢国章.微机械的制造、应用和发展[J].中国机械工程,1994,5(3):64-66. 被引量:6
  • 2李山云,林奇,李维强.基因芯片技术及其在食品工业中的应用[J].食品与机械,2005,21(4):72-75. 被引量:9
  • 3刘兵,徐立鸿,冯纯伯.具有饱和输入的预测控制的稳定性分析[J].控制理论与应用,1997,14(2):178-183. 被引量:7
  • 4Reymond P,et al.Differential gene expression in response to mechanical wounding and insect feeding in Arabidopsis.Plant Cell,2000,12,707-720.
  • 5陈受宜 张劲松 张志刚等.通过eDNA微阵列鉴定水稻(Oryza sativa L,)盐胁迫应答基因.中国科学:C辑,2006,6:10-15.
  • 6Robert S,Jeff L,,monica A,et al.Microarray Analysis of Diurnal and Cireadian-Regulated Genes in Arabidopsis.The Plant Cell,2001,13:113-123.
  • 7Borucki M K,Krug M J,Muraoka W T,et al.Discrimination among Listeria monocytogene isolates using a mixed genome DNA microarray[J].VeterioaryMicrobiol,2003,92 (4):351-342.
  • 8An H J,Cho N H,Lee S Y,et at.Correlation of Cervical Carcinoma and Precancerous Lesions with Human Papilloma Virus (HPV) Genotypes Detected with the HPV I)NA Chip Microarray Method[J].Cancer,2003,97(7):1 672-1 680.
  • 9Krug A,Tonissen N,Georgiou l,et al.Arrayed Primer extension:solid -phase four-color DNA resequencing and mutation detection technolog,y[J].Genet Test,2000,4(1):1.
  • 10Joos T O,Schrenk M,Hopfi P,et at.A microarray enzyme -linked immunoso-rbent assay for autoimmune diagnostics.Electrophoresis,2000,21(13):2641-2650.

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