摘要
目的 为了更好地诊治老年带状疱疹 ,尽量减少和减轻后遗症。 方法 对 1996年 8月～ 1999年 3月诊治的 6 9例老年带状疱疹进行回顾性分析、研究。 结果 6 9例老年带状疱疹患者均发生神经病 ,5 3例 (占76 8% )感觉剧痛 ,3 3例 (占 47 8% )有后遗神经痛 ,其中 5例的疼痛持续时间在 6 0d以上。 5例合并恶性肿瘤 ,这 5例患者的皮疹分布均比较广泛 ,且均属于特殊类型。采用病毒抑制剂阿昔洛韦治疗 3 7例、万乃洛韦治疗 3 2例 ,2组的总有效率无显著差异 (P >0 0 5 ) ,而万乃洛韦组的痊愈率则显著高于阿昔洛韦组 (P <0 0 5 )。 结论 对老年带状疱疹 ,早期使用足够剂量、足够疗程的抗病毒药是必要的 ,对神经痛应该采取综合性的治疗措施 ;同时要警惕合并恶性肿瘤的可能性。
In order to ameliorate the treatment and decrease the sequelae of senile herpes zoster. Methods 69 cases of senile herpes zoster treated from August 1996 to May 1999 had been investigated retrospectively. Results Neuralgia was noticed in all of the cases,and severe pain was noticed in 53 cases(76 8%).Posttherapeutic pain was experienced in 33 cases (47 8%),and the pain was existed above 60 days in 5 cases.5 cases associated with malignant tumors,the distribution of skin lesions was rather extensive,and all belonged to the special type.Acyclovir was treated in 37 cases,and valacyclovir in 32 cases.The total effective rates between these 2 groups showed no significant difference( P >0 05).The cure rate of valacyclovir was significantly higher than that of acyclovir( P <0 05). Conclusions Early application of sufficient dose and sufficient course of antiviortic agents is necessary for senile herpes zoster.Complex therapeutic measures should be applied promptly for neuralgia,and at the same time pay attention to the possibility of association of malignant tumors.
出处
《实用老年医学》
CAS
1999年第6期304-305,共2页
Practical Geriatrics
