鲍曼不动杆菌医院内下呼吸道感染危险因素配比病例对照研究

A Metched Case control Study on Risk Factors of Infection of down Respiratory Tract Caused by Acinetobacter Baum/haec

采用１∶１ 配比病例对照研究方法，将９４ 例临床确诊为鲍曼不动杆菌医院下呼吸道感染的病例，同时配以感染对照和非感染对照进行分析，探讨鲍曼不动杆菌医院下呼吸道感染危险因素⒚多因素Ｌｏｇｉｓｔｉｃ 回归分析表明：病例和非感染病例比较显示，病情危重、气管插管、机械通气、雾化吸入、３ 种以上抗生素疗程超过２ 周、ＣＯＰＤ、重症监护和化疗为鲍曼不动杆菌医院下呼吸道感染的危险因素；病例与感染病例对照比较，则气管切开、机械通气、雾化吸入、重症监护为鲍曼不动杆菌医院下呼吸道感染独立的危险因素⒚单因素分析还发现原先有肺部感染和插胃管与鲍曼不动杆菌医院下呼吸道感染有关（Ｐ＜ ０．

A metched case control study with two kind of controls(infection controls and non infection controls) was conducted among 94 hospitalized patients to investigate risk factors of nosocomial infection of down respiratory tract caused by acinetobacter Baum/haec.The multivariable conditional logistic regression analysis show that severity of illness on admission,tracheostomy,mechenical ventilation,use of nubulizer,previous antibiotics usage ≥2 weeks,COPD antecedent,expose to intensive care uite,chemotherapy were independent risk factor of nosocomial pneumonia caused by Acinetobacter baum/haec.