摘要
A series of Andro derivatives were described and evaluated for their anti-HIV activity in vitro. Compound 10 and 16b, of which TI were 〉 10, had some anti-HIV-1 activity in vitro. Therein, compound 10 which was the best potent compound, could serve as a new lead for further development of anti-AIDS agents.
A series of Andro derivatives were described and evaluated for their anti-HIV activity in vitro. Compound 10 and 16b, of which TI were 〉 10, had some anti-HIV-1 activity in vitro. Therein, compound 10 which was the best potent compound, could serve as a new lead for further development of anti-AIDS agents.
基金
supported by the National Natural Science Fundation of China(No.30772647)
the special major science and technology project of"Creation of Major New Drugs"(No.2009ZX09102-033)
