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Cu(OTf)2 Catalyzed Synthesis of Bis(5-methyl-2-furyl)methanes by Condensation of 2-Methylfuran with Carbonyl Compounds under Solvent Free Conditions

Cu(OTf)2 Catalyzed Synthesis of Bis(5-methyl-2-furyl)methanes by Condensation of 2-Methylfuran with Carbonyl Compounds under Solvent Free Conditions
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摘要 A facile and efficient one-pot three-component synthesis of bis(5-methyl-2-furyl)methanes has been achieved via the reaction of 2-methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper(II) triflate under solvent free conditions. The bis(5-methyl-2-furyl)methanes were obtained in 34%--72% yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity. A facile and efficient one-pot three-component synthesis of bis(5-methyl-2-furyl)methanes has been achieved via the reaction of 2-methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper(II) triflate under solvent free conditions. The bis(5-methyl-2-furyl)methanes were obtained in 34%--72% yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2011年第7期1483-1488,共6页 中国化学(英文版)
关键词 Lewis acid copper(II) triflate 2-METHYLFURAN bis(5-methyl-2-furyl)methane multicomponent condensation solvent free condition Lewis acid, copper(II) triflate, 2-methylfuran, bis(5-methyl-2-furyl)methane, multicomponent condensation, solvent free condition
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