心血管疾病患者合并肺部感染的病原菌及耐药性分析

Pathogens and drug resistance analysis of pulmonary infection in patients with cardiovascular disease

目的研究心血管患者合并肺部感染的病原菌及耐药情况。方法对252例心血管疾病合并肺部感染患者的痰标本进行细菌培养和菌种鉴定,并作药敏测定。结果肺部感染以G-杆菌居多(70.91%),其中肺炎克雷伯菌为最主要的致病菌;G+球菌其次(19.63%);真菌占9.46%。药敏试验显示:大多数G-杆菌对广谱抗生素耐药,对碳青霉烯类、阿米卡星有较高的敏感性;G+球菌对替考拉宁、万古霉素等有较高敏感性,其余耐药性差异大。结论临床上应根据病原菌对抗菌药物的敏感性及耐药性特征,合理选用抗菌药物。

Objective To study the pathogens and drug resistance of pulmonary infection in patients with cardiovascular disease.Methods The sputum specimens for bacterial culture and strain identification,and determination of drug susceptibility of 252 cases of pulmonary infection in patients with cardiovascular disease with were detected.Result The pulmonary infection was most G-bacilli（70.91%）,Klebsiella pneumoniae as the most important pathogens.G＋ cocci followed（19.63%） and Fungi was 9.46%.Sensitivity test showed that the majority of G-bacilli to broad-spectrum antibiotic resistance,the rate of drug sensitivity to carbapenems and amikacin were quite high.G＋ cocci had high drug sensitivity to Teicoplanin and Vancomycin,there were different sensitivity in others.Conclusion According to the sensitivity and drug resistance of the pathogens to antibiotics in clinical,the antibiotics should be reasonable choice.