乌司他丁对重症急性胰腺炎患者动脉血乳酸和预后的影响

目的:观察乌司他丁对重症急性胰腺炎患者动脉血乳酸和预后的影响。方法:48例重症急性胰腺炎患者随机分为2组,A组(22例)进行一般治疗,B组(26例)加用乌司他丁,比较两组患者住院期间血乳酸平均水平和30天内死亡率。结果:A组患者住院期间动脉血乳酸平均水平和死亡率均高于B组。结论:加用乌司他丁可以降低重症急性胰腺炎患者血乳酸水平,改善预后。

Objective：To survey the effection of ulinastatin on arterial lactic acid and prognosis in patients with severe acute pancreatitis. Method ：48 cases with severe acute pancreatitis were randomly divided into 2 goups ： group A （ n = 22 ） were applied with regular treatment, while group B （ n = 26 ） were applied with regular treatment plus ulinastatin intravenous injection. Arterial lactic acid in duration of hospital stay and mortality were compared between the 2 groups. Outcome Arterial lactic acid in duration of hospital stay and mortality in group A were relatively higher than group B. Conclusion： Ulinastatin addiction treatment could cut down the arterial lactic acid and ameliorate prognosis in patients with severe acute pancreatitis.