酚妥拉明联合银杏达莫治疗慢性肺源性心脏病疗效观察

Phentolamine plus Ginkgo Dipyridamole Injection for Chronic Pulmonary Heart Disease

目的:观察酚妥拉明联合银杏达莫对慢性肺源性心脏病心衰患者的疗效,为临床治疗提供依据。方法:将90例患者随机分为治疗组和对照组各45例。两组采用常规内科治疗如控制感染、氧疗、强心、利尿等,治疗组在上述治疗基础上加用酚妥拉明20mg+银杏达莫25 mL于10%葡萄糖注射液500 mL中静脉滴注,1次/d,疗程均为10 d。结果:治疗组的疗效、血气分析、血液流变学、功能的改善优于对照组,差异具有统计学意义(P<0.05)。结论:酚妥拉明联合银杏达莫对慢性肺源性心脏病心衰患者具有良好的疗效及安全性,值得临床推广应用。

Objective： To observe the clinical effect of phentolamine combined with ginkgo dipyridamole injection in the treatment of chronic pulmonary heart disease with heart failure.Methods： A total of 90 patients were randomly divided into control group （n=-45） and therapy group （n=45）.Two groups were treated with medical treatment such as control infection, oxygentherapy, cardiotonic and diuresis.On the basis of the above therapy, the treatment group were added phentolamine 20 mg combined with ginkgo dipyridamole injection 25 mL with 10% Glucose 500 ml in intravenous drip, quotidie, 10 days for a course of treatment. Results： The therapeutic effect, results of blood gas analysis and blood rheology, and heart function in therapy group were better than the control group, with statistically significant difference （ P 〈 0.05）. Conclusion： Phentolamine combined with ginkgo dipyridamole injection in treatment of chronic pulmo- nary heart disease with heart failure is effective and safe. It deserves to be popularized.