超选择性肾动脉栓塞术联合射频消融治疗肾癌的临床应用

Superselective renal artery embolization combined with radiofrequency ablation for the treatment of renal carcinomas:evaluation of clinical results

目的探讨超选择性肾动脉栓塞术联合射频消融(RFA)治疗肾癌的疗效。方法分析2009年1月至2011年4月9例肾癌患者超选择性肾动脉栓塞联合RFA。患者均在超选择性肾动脉栓塞术后3～7 d,在CT引导下行RFA。术后1个月行肾脏病灶穿刺活检和CT增强检查评价其疗效。结果 9例患者随访1～6个月,未发现肾脏肿瘤增大,无周围脏器损伤和针道种植。RFA后出现肉眼血尿6例,1周后好转,肾功能治疗前后无明显变化。治疗效果显示部分缓解6例,无变化3例。结论超选择性肾动脉栓塞联合RFA治疗肾癌短期内疗效肯定,并发症少,是肾癌的一种安全有效的治疗手段。

Objective To evaluate superselective renal artery embolization combined with radiofrequency ablation in treating renal carcinomas.Methods During the period from Jan.2009 to April 2011,superselective renal artery embolization combined with radiofrequency ablation was carried out in 9 cases with renal cell carcinoma.Under CT guidance,radiofrequency ablation was conducted 3-7 days after superselective renal artery embolization was accomplished.One month after the treatment renal lesion biopsy and contrast-enhanced CT scanning were employed to estimate the clinical results.Results All the patients were followed up for 1-6 months.During the follow-up period,enlargement of renal tumor,injury of para-renal visceral organs and needle tract malignant implantation were not found.After radiofrequency ablation six patients developed hematuria,that subsided in one week.Renal function showed no obvious changes after the treatment.Partial alleviation was seen in six patients and the clinical condition was unchanged in another three patients.Conclusion For the treatment of renal carcinomas,superselective renal artery embolization combined with radiofrequency ablation has reliable short-term effects with fewer complications.Therefore,this technique is an effective and safe treatment.