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舒尼替尼治疗恶性胰岛细胞瘤疗效初探 被引量：2

Therapeutic potential of sunitinib in the treatment of malignant islet cell tumor
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摘要 恶性胰岛细胞瘤是一种少见但治疗效果欠佳的神经内分泌肿瘤.舒尼替尼作为新一代的酪氨酸激酶抑制剂,已被证实对于恶性胰岛细胞瘤具备较好的疗效. Malignant islet cell tumor, a rare type of neuroendocrine carcinoma, biologically behaves in an aggressive way and is difficulty to be treated. Sunitinib malate, a novel tyrosine kinase inhibitor, demonstrates a high efficacy in treating malignant islet cell tumor as shown by promising results in recent trials.
作者 汪劭婷 李乃适
机构地区 中国医学科学院 北京协和医学院 北京协和医院内分泌科
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2011年第7期618-620,共3页 Chinese Journal of Endocrinology and Metabolism
关键词 舒尼替尼 恶性胰岛细胞瘤 Sunitinib malate Malignant islet cell tumor
分类号 R736.7 [医药卫生—肿瘤]
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参考文献30

  • 1Raoul JL, Niccoli P, Bang YJ. Sunitinib(SU) vs placebo for treatment of progressive, well-differentiated pancreatic islet cell tumours: results of a phase Ⅲ, randomised, double-blind triM. Eur J Cancer Suppl, 2009,7:361.
  • 2Oberg K, Eriksson B. Endocrine tumours of the pancreas. Best Pract Res Clin Gastroenterol, 2005,19:753-781.
  • 3Rinke A, Muller HH, Schade-Brittinger C, et al. Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors : a report from the PROMID Study Group. J Clin Oncol, 2009,27:4656-4663.
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同被引文献13

  • 1陆新良,王小英,钱可大,吴勤动.WERMER综合征一例[J].中华内科杂志,2006,45(1):63-64. 被引量：2
  • 2Oberg K,Eriksson B.Endocrine tumours of the pancreas[J].Best Pract Res Clin Gastroenterol,2005,19(5):753-781.
  • 3Kouvaraki MA,Solorzano CC,Shapiro SE,et al.Surgical treatment of non-functioning pancreatic islet cell tumors[J].J Surg Oncol,2005,89(3):170-185.
  • 4Cryer PE,Axelrod L,Grossman AB,et al.Evaluation and management of adult hypoglycemic disorders:an endocrine society clinical practice guideline[J].J Clin Endocrinol Metab,2009,94(3):709-728.
  • 5Rinke A,Muller HH,Schade-Brittinger C,et al.Placebocontrolled,double-blind,prospective,randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors:a report from the PROMID Study Group[J].J Clin Oncol,2009,27(28):4 656-4 663.
  • 6Rigaud G,Missiaglia E,Moore.PS,et al.High resolution allelotype of nonfunctional pancreatic endocrine tumors:identification of two molecular subgroups with clinical implications[J].Cancer Res,2001,61(1):285-292.
  • 7Kulke MH,Lenz HJ,Meropol NJ,et al.Activity of sunitinib in patients with advanced neuroendocrine tumors[J].J Clin Oncol,2008,26(20):3403-3410.
  • 8赵玉沛.恶性胰腺内分泌肿瘤的诊断与肝转移的外科治疗[J].腹部外科,2008,21(5):272-273. 被引量：6
  • 9胰腺内分泌肿瘤的诊断和外科治疗指南（讨论稿）[J].中华外科杂志,2009,47(5):339-341. 被引量：14
  • 10展翰翔,赵玉沛,张太平,丛林,廖泉,戴梦华.胰岛素瘤患者围手术期血糖变化规律及处理[J].中华肝胆外科杂志,2011,17(1):13-16. 被引量：5

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中华内分泌代谢杂志
2011年 第7期

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