益气活血方在晚期食管癌综合治疗中的作用

Clinical Observation on Effect of Yiqi Huoxue Decoction in Comprehensive Treatment on Advanced Stage of Esophageal Cancer

目的 :探讨益气活血方在食管癌患者放化疗中的作用。方法 :62例食管癌患者随机分为两组 ,31例行放疗和介入化疗 (A组 ) ,与 31例放疗、介入化疗和益气活血方并用 (B组 )进行比较。结果 :A、B两组近期有效率为 48 4%、64 5 % (P >0 0 5 ) ,B组骨髓功能明显高于A组 (P <0 0 1)。 1年转移率A组高于B组 (P <0 0 5 ) ,远期生存率B组明显高于A组 (P <0 0 5 )。结论 :本方能减轻放化疗造成的骨髓抑制 ,降低转移率 ,延长远期生存率 ,改善生活质量。

Objective: To observe the effect of Yiqi Huoxue (Replenishing Qi and activating blood circulation, YQHX) decoction in patients with advanced stage esophageal cancer treated with radiotherapy (RT) and intervention chemotherapy (ICT). Methods: In comparing 31 patients who were treated with RT and ICT (Group A), and 31 patients treated with RT and ICT plus YQHX decoction (Group B). Results: Immediate effective rate were 48.4% in Group A and 64.5% in Group B (P>0 05). The function of bone marrow in Group B was obviously higher than that in Group A. The 1 year metastasis rate in Group A was higher than that in Group B, but the long term survival rate of Group B was obviously higher than that in Group A (P<0 05). Conclusion: YQHX decoction could reduce the inhibition of bone marrow caused by radiotherapy and intervention chemotherapy, lower the metastasis rate, prolong the long term survival rate and improve the quality of life.