经皮椎体成形术联合金乌骨通治疗椎体骨质疏松性骨折

Vertebral Osteoporotic Fractures Were Treated by Percutaneous Vertebroplasty and Jinwugutongjiaonang

目的:评价经皮椎体成形术(percutaneous vertebroplasty,PVP)联合金乌骨通治疗椎体骨质疏松性骨折的临床疗效。方法:将135例椎体骨质疏松性骨折患者(146椎体),随机分为两组,其中治疗组行PVP联合金乌骨通胶囊治疗74例,对照组单独应用pvp治疗61例,分别记录病人入院时、术后24h、4周、6个月疼痛缓解情况、行走能力、骨折愈合、远期再发骨折及骨密度情况。结果:所有手术均顺利完成,未发生明显并发症,治疗组与对照组比较,病人在术后疼痛缓解情况、行走能力、骨折愈合、远期再发骨折及骨质疏松情况的改善方面比较差异均有统计学意义(P<0.05)。结论:PVP联合金乌骨通胶囊治疗椎体骨质疏松性压缩骨折对患者的疼痛缓解、骨折愈合、预防再发骨折、改善骨质疏松状况等方面均有较好的疗效,值得临床推广应用。

Objective：To evaluate the clinical efficacy of percutaneous vertebroplasty（percutaneous vertebroplasty,PVP） combined with Jinwugutongjiaonang in treating of vertebral osteoporotic compression fractures.Methods：135 patients（146 vertebras） who suffered with vertebral osteoporotic compression fractures were randomly divided into two groups,patients（74 cases） in the treatment group were treated by PVP combined with Jinwugutongjiaonang,patients（61 cases） in the control group were treated by PVP,the pain relief,the ability of walking,fracture healing,long-term recurrence of fracture and bone mineral density were recorded separately on admission,24 hours、4 weeks and 6 months postoperation for all the patients.Results：All operations were successfully completed,and no obvious complications happened.There were significant differences in the pain relief,the ability of walking,fracture healing,long-term recurrence of fracture and bone mineral density between the treatment group and control group（P0.05）.Conclusion：There was good clinical efficacy in the pain relief,fracture healing,long-term recurrence of fracture and bone mineral density for the patients with vertebral osteoporotic compression fractures treated by Percutaneous vertebroplasty（PVP） combined with Jinwugutongjiaonang,and It was worthyof application for clinic.