肝硬化患者43例血气分析变化

Blood gas analysis in 43 cases of patients with hepatic cirrhosis

目的探讨肝硬化患者血气分析变化的临床意义。方法回顾性分析43例肝硬化患者血气分析资料。结果①肝硬化酸碱失衡的发生率为74.4%,以单纯性呼吸性碱中毒最多见,发生率为23.3%;②C级患者中多重酸碱失衡发生率为57.2%,与A级患者比较,差异有统计学意义(P<0.05);③肝硬化患者低氧血症总发生率为55.8%,与A级、B级比较,C级发生率明显升高(P<0.05)。结论①肝硬化患者以呼吸性碱中毒最常见,C级患者更易合并多重酸碱失衡;②肝硬化患者低氧血症发生率高,并随着Child-Pugh分级的增高而上升。应动态监测血气分析情况,及时对症治疗,进一步提高肝硬化患者的生存质量。

Objective To investigate the changes of blood gas analysis in patients with hepatic cirrhosis.Methods The blood gas analysis in 43 patients with hepatic cirrhosis were analyzed.Results ①The incidence of acid base disturbance in patients with hepatic cirrhosis was 74.4%,respiratory alkalosis was the most common type,the incidence was 23.3%;②The incidence of compound acid base disturbance in patients of Child-Pugh C was 57.2%.There was significant difference when compared with those of Child-Pugh A（P0.05）;③The incidence of hypoxemia in patients with hepatic cirrhosis was 55.8%.Compared to Child-Pugh A and B,the incidence of hypoxemia in Child-Pugh C was apparently higher（P0.05）.Conclusion ①Among acid base disturbance cases,the incidence of simple respiratory alkalosis is the highest in patients with hepatic cirrhosis.Compound acid base disturbance often occurs in advanced Child-Pugh C patients;②The incidence of hypoxemia was high in patients with hepatic cirrhosis.The incidence of hypoxemia was increased along with Child-Pugh classification increasing.Dynamically monitoring the changes of arterial blood was helpful for the therapy,prognosis of the patients.