肺癌患者下呼吸道病毒抗原检测

The detection of virus antigen in the lower respiratory tract of the patients with lung cancer

目的 了解肺癌患者下呼吸道病毒感染情况。方法 通过纤维支气管镜刷取肿物周围之分泌物,采用北京军区第262医院研制的呼吸道病毒抗原检测试剂盒进行检测、分析。结果 肺癌组呼吸道病毒抗原阳性8例,阳性率174%(846),显著高于非肺癌组(P<005)。其中甲型流感病毒1例,乙型流感病毒2例,副流感病毒(1,3型)2例,腺病毒2例,呼吸道合胞病毒1例。鳞癌、小细胞癌、腺癌伴病毒感染依次为4例、3例、1例。结论 肺癌与常见呼吸道病毒感染有统计学上的相关性,肺癌患者感染率增加,值得重视。

Objective To find out about the viral infection situation of lower respiratory tract of the patients with lung cancer. Methods The excretion from the surface of bronchiogenic carcinoma was brushed under fibrobronchoscopy. The respiratory virus antigen was detected and analysed by reagent kit produced by the 262nd Hospital of Beijing Military Region.Results The respiratory virus antigen was positive in eight cases of lung cancer group, the positive rate was 17.4%(8/46), it was significantly higher than that in non lung cancer group ( P <0.05). Among them, there were one case of influenza virus A, two cases of influenza virus B, two cases of para influenza 1,3, two cases of adenovirus and one case of respiratory syncytial virus. The carcinoma accompanied with viral infection were 4,3,1, cases in order of sqamous carcinoma, small cell lung carcinoma and adenocarcinoam.Conclusion The results showed that a relationship existed between lung cancer and viral infection of respiratory tract statistically. The viral infection increased in patients with lung cancer, this is worthy to pay attention to.