PRK治疗近视术后激素性高眼压分析

STEROID-INDUCED OCULAR HYPERTENSION FOLLOWING PRK FOR MYOPIA

目的 :分析准分子激光角膜切削术 ( PRK)治疗近视术后激素性高眼压的发生及预后。方法 :回顾性分析近视度数在 - 1 .75D到 - 1 9D的 91眼的激素性高眼压的发生及治疗情况 ,并与对照组做比较。结果 :激素性高眼压的发生率为 3.88% ,眼压升高多发生于术后 2月 ,男性多于女性。眼压升高时平均眼压 3.87± 0 .74k Pa,治疗后在 1 2 .2 3± 7.39d内眼压恢复正常。术后最后一次随访时裸眼视力为 1 .1 2± 0 .34( 0 .2～ 1 .5) ,剩余屈光度为 - 0 .61± 1 .1 0 ( - 3.50～ + 1 .2 5) DS。眼压升高组与对照组相比术前平均眼压高 ,角膜较厚 ,角膜屈光力较平坦。结论 :定期术后随访可及时发现激素性高眼压 ,治疗后不影响视力预后。术前认真筛选可疑病人和修订激素性青光眼的诊断标准有助于提高

Objective:To analyze the occurrence and prognosis of the steroid induced ocular hypertension following photorefractive keratectomy(PRK) for the treatment of myopia Methods:Ninty One eyes ranging from -1 75D to -19D which developed ocular hypertension after PRK was retrospectively analyzed and compared with the control group Results: The occurrence rate of steroid induced ocular hypertension was 3 88%, and it occurred mostly at two months after the surgery and male was more likely developed than female The mean IOP was 3 87±0 74kPa when IOP was at its highest point, after appropriate treatment it reduced to normal At the last visit mean uncorrected visual acuity was 1 12 ± 0 34(0 2~1 5) and remained refractive error was 0 61±1 10(-3 50 ~ +1 25)DS Baseline IOP, corneal depth, and corneal refractive power was different among the steroid-induced hypertension group compared to the control Conclusion: Steroid induced ocular hypertension can be timely detected and treated when follow up was at regular intervals and prognosis was good Screening of high risk patient and calibration of diagnosis standard may contribute to the safety of PRK for myopia