纤维蛋白原和血液粘滞度的改变与肺心病肺动脉栓塞相关性的探讨

THE CORRELATION OF FIBRONIGEN AND BLOOD VISCOSITY WITH COR PULMONARY EMBOLISM

目的 :探讨纤维蛋白原和血液粘滞度与慢性阻塞性肺心病肺动脉血栓栓塞的关系。方法 :对 46例肺心病急性发作期纤维蛋白原、血液粘滞度进行了测定及观察肝素治疗后的变化。结果 :肺心病急性发作期纤维蛋白原、血液粘滞度均增高 ,肝素治疗后降低。结论 :肺心病纤维蛋白原、血液粘滞度增高造成血液凝固性升高是肺心病肺动脉血栓栓塞的一个重要原因。肝素治疗能减轻高凝状态 。

Objective : To investigate the relationship of fibrinogen(Fb) and blood Viscosity(BV) in pulmonary embolism and thrombosis with cor pulmonary of COPD Methods:46 cor pulmonary patients were checked with Fb and BV during the acute attack phase before and after treatment Results:The value of Fb and BV are significantly higher than of control groop p <0 01 BV significantly lower after freatment with heparin Conclusion: It indicated that higher level Fb and BV can increase the blood coagulability It is an important cause of the pulmonary embolism and thrombosis in corpulmonary Heparin can decrease the high coagulate state and prevent the attack of pulmonary embolism and thrombosis