血流储备分数测定中最大充血相诱发药物的应用

Pharmacological Options for Inducing Maximal Hyperaemia During Studies of Fractional Flow Reserve

血流储备分数作为冠状动脉狭窄功能性评价的指标已广泛应用于临床。在血流储备分数的测定中必须用药物来诱发最大充血相。现就血流储备分数的测定中所用的最大充血相诱发药物进行综述,讨论各种药物的特点及这方面药物的一些进展。

Measurement of fractional flow reserve（FFR） is a widely used technique in cardiac catheterisation laboratories to determine the functional significance of coronary artery stenoses.The achievement of maximal hyperaemia is a prerequisite for the accurate determination of FFR.This article focuses on the pharmacological agents that can be used for this purpose,discusses which agents can be used in specific situations,and briefly addresses the future of pharmacological stress in the catheter laboratory.