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卡维地洛治疗儿童心血管系统疾病的研究进展 被引量：4

Mechanism of Carvedilol in Treatment of Cardiovascular Disease in Children
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摘要 卡维地洛(carvedilol)是一种新型的非选择性肾上腺素能受体阻滞剂,具有β受体和α受体双重阻滞、调节细胞因子、抗氧化、抗心脏重构和抗心律失常等多方面的作用,无内在拟交感活性,避免了反射性交感神经兴奋所引起的周围血管收缩及外周阻力增加,通过减轻心肌炎症,延缓并逆转心室重构,改善血流动力学,改善预后。目前关于卡维地洛治疗或干预儿童病毒性心肌炎、扩张型心肌病、心律失常已逐渐受到重视。现对卡维地洛治疗儿童心血管系统疾病研究进展做一综述。 Carvedilol can inhibit β-receptor and α-receptor,regulate cytokine,and has antioxidant,antiremodeling and antiarrhythmia actions.Carvedilol is currently the treatment,or intervention,used for children with viral myocarditis,dilated cardiomyopathy,and cardiac arrhythmia.This paper reviews the mechanism of carvedilol in patients,particularly children,with cardiovascular diseases.
作者 王丽燕 王文棣
机构地区 青岛市妇女儿童医院内科
出处 《心血管病学进展》 CAS 2011年第4期607-609,共3页 Advances in Cardiovascular Diseases
关键词 卡维地洛 儿童心血管系统疾病 研究进展 carvedilol children with cardiovascular diseases research progress
分类号 R725.4 [医药卫生—儿科] R54 [医药卫生—心血管疾病]
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参考文献37

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二级参考文献70

共引文献124

同被引文献52

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引证文献4

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心血管病学进展
2011年 第4期

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