小剂量高渗盐水在早期创伤失血性休克的疗效评价

EVALUATION OF EFFICACY OF SMALL-DOSES HYPERTONIC SALINE IN THE EARLY TRAUMATIC HEMORRHAGIC SHOCK

目的评价小剂量高渗盐水在早期创伤失血性休克的疗效。方法将符合早期创伤失血性休克96例患者随机分为小剂量高盐渗水复苏组(治疗组)和传统液体复苏组(对照组)。对两组患者的复苏时间、复苏前后收缩压、胶体液量、总输液量、ARDS、(MODS)的发生率、死亡率等进行统计学分析。结果两组的组间复苏时间、复苏前后收缩压等无显著差异性(p>0.05)。治疗组复苏液体总量明显小于对照组[(1 206±318)ml vs(1 989±735)ml,p<0.05],其ARDS、MODS、死亡率均低于对照组(ARDS 4 vs 9,MODS 8 vs 16,死亡率12%vs 28.26%,p<0.05)。结论小剂量高渗盐水复苏可以减少在早期创伤失血性休克的输液量、减少并发症及死亡率。

Objective To evaluate low doses of hypertonic （ small - doses hypertonic） saline in the early traumatic hemorrhagic shock efficacy. Methods Divide 96 patients with early traumatic hemorrhagic shock into two groups ： treatment group, control group. Analysis the heart rate, recovery time, systolic blood pressure before and after recovery, the total infusion volume, ARDS, MODS, mortality of the two groups. Results There is no obvious difference between Recovery time any systolic blood pressure before or after recovery（p 〉 0. 05 ）. Total amount of saline fluid resuscitation was significantly lower than control group[ （ 1 206± 318 ） ml vs （ 1 989 ± 735 ） ml, p 〈 0.051, the ARDS, MODS, mortality rates were lower than the control group （ ARDS4vs 9, MODS8 vs 16, mortality 12% vs 28.26%, p 〈 0. 05）. Conclusions Small dose hypertonic saline resuscitation reduces the early traumatic hemorrhagic shock in the fluid volume,Reduce complications and mortality.