抗高血压药物的临床使用分析

Analysis of the usage of anti-hypertension drugs

目的 分析大连大学附属中山医院2007-2009年抗高血压药使用情况,为合理使用抗高血压药提供参考.方法 利用医院药库计算机网络管理系统收集大连大学附属中山医院2007年1月至2009年12月抗高血压药的出库销售数据,采用医院药品用药频度排序分析原理进行分类、统计、分析数据.结果 大连大学附属中山医院抗高血压药占全院药品销售总金额的比例逐年上升,3年平均比例为0.13%.钙离子通道阻滞药用药频度一直处于第1位,年平均增长率175.27%;β受体阻滞药居第2位,年增长率141.86%;血管紧张素Ⅱ受体阻滞药、血管紧张素转化酶抑制药、利尿药年平均增长率依次为第3、4、5位,年 增长率分别为117.50%、46.94%、42.66%.而用药金额、用药频度最高的药品为钙离子通道阻滞剂.结论 大连大学附属中山医院抗高血压药的应用状况与国内其他城市的医院总体用药基本相同.其临床使用的总体水平正朝着趋于合理的方向发展.

Objective To analyze the usage of anti-hypertension drugs at Zhongshan hospital affiliated to Dalian university during 2007-2009, and to provide medical reference for the rational use of anti-hypertension drugs. Methods The sales data of anti-hypertension drugs was collected by the hospital medical storehouse computer management system from January 2007 to December 2009. Meanwhile the hospital drugs defined daily dosages （DDDs） sorting principle was used for the analysis in this study. Results The sales proportion of the anti-hypertension drugs among all drugs has been increasing over the three-year period. The average annual proportion was 0. 13%. The DDDs of calcium antagonists was in the first place, with an average annual growth rate of 175. 27%. β-receptor blockers was in the second place, with an average annual growth rate of 141.86%. Angiotensin Ⅱ receptor blocker （ARB） , angiotensin-converting enzyme inhibitors（ACEI） , and diuretics were in the third, fourth and fifth place respectively. The highest frequency of drug usage was the calcium channel blockers. Conclusion The usage of antihypertension drugs in the Zhongshan hospital affiliated to Dalian university is moving towards the reasonable direction.