期刊文献+

乳腺癌治疗前后血浆D-二聚体水平变化及其临床意义 被引量:2

The Level of Plasma D-dimer Pre-and Post-Treatment in Patients with Breast Cancer and its Clinical Significance
原文传递
导出
摘要 [目的]探讨乳腺癌患者治疗前后血浆D-二聚体水平变化及其临床意义。[方法]测定95例乳腺癌患者及80例乳腺良性肿瘤患者治疗前后的血浆D-二聚体水平。[结果]治疗前乳腺癌组的血浆D-二聚体水平高于乳腺良性肿瘤组,差异有显著统计学意义(P〈0.01);治疗前有淋巴结转移乳腺癌患者血浆D-二聚体水平高于无淋巴结转移患者(P〈0.05),临床Ⅰ~Ⅱ期患者血浆D-二聚体水平低于Ⅲ期患者(P〈0.05)。乳腺癌患者治疗后血浆D-二聚体水平低于治疗前(P〈0.05)。[结论]血浆D-二聚体水平检测在乳腺癌患者的病情评估、疗效观察、预后判断等方面具有重要的临床应用价值。
出处 《肿瘤学杂志》 CAS 2011年第6期469-470,共2页 Journal of Chinese Oncology
  • 相关文献

参考文献4

  • 1Samama MM, Horellou MH, Elalamy I, et al. D-dimer lev- els, constitutional thrombophilia, and venous thrombosis prediction: clinical aspects and implications [J]. Semin Vasc Med, 2005, 5(4):371-374.
  • 2戴庆忠,覃瑜.恶性肿瘤患者凝血指标检测的临床意义[J].检验医学与临床,2009,6(5):347-348. 被引量:14
  • 3Ay C, Vormittag R, Dunkler D, etal. D-dimer and pro- thrombin fragment 1 +2 predict venous thromboembolism in patients with cancer: results from the Vienna cancer and thrombosis study [J]. J Clin Oncol, 2009, 27 (25): 4124-4129.
  • 4张璐,胡豫,孙春艳,黄靖.乳腺癌患者凝血功能的改变及意义[J].血栓与止血学,2007,13(5):223-225. 被引量:7

二级参考文献14

  • 1樊锡凤,冯忠军,赵文君,张晶晶,武湘云,孙桂兰.恶性肿瘤患者检测血浆纤维蛋白原的临床意义[J].河北医科大学学报,2005,26(3):215-216. 被引量:9
  • 2张丽中,赵智,吴滨.恶性肿瘤患者血浆纤维蛋白原和D二聚体含量的测定及其临床意义[J].肿瘤研究与临床,2006,18(11):759-760. 被引量:25
  • 3许玉成 刘淑真 刘丙奎.血小板增多与恶性肿瘤[J].癌症,1985,4(3):159-161.
  • 4[1]MESSMORE H.Hemostasis in malignancy[J].Am J Haemato,1990,35(1):4546.
  • 5[2]POLITE BN,LAMONT EB.Are venous thromboembolic events associated with subsequent breast and colorectal carcinoma diagnoses in the elderly? A case-control study of Medicare beneficiaries[J].Cancer,2006,106(4):923-930.
  • 6[3]MEHTA P.Potential role of platelet in the pathogenesis of tumor metastasis[J].Blood,1981,63 (1):55-58.
  • 7[5]FALANGA A,LEVINE MN.The effect of very-low-dose warfarin on markers of hypercoagulation in metastatic breast cancer:results from a randomized trial[J].Thromb Haemost,1998,79(1):23-27.
  • 8[6]WADA H,SASE T,YAMAGUCHI M.Hypercoagulant states in malignant lymphoma[J].Exp Oncol,2005,27 (3):17-21.
  • 9[7]SAMAMA MM,HORELLOU MH,ELALAMY I,et al.D-dimer levels,constitutional thrombophilia,and venous thrombosis prediction:clinical aspects and implications[J].Semin Vasc Med,2005,5(4):371-377.
  • 10张培彤,裴迎霞,朴炳奎,孙桂芝,林红生,祁鑫.肿瘤患者与正常人血小板表面粘附蛋白表达异同的临床观察及意义[J].中华肿瘤杂志,1998,20(3):207-209. 被引量:66

共引文献19

同被引文献22

  • 1钮心怡,周盛杰,陈泽英.肝癌患者纤维蛋白原和D-二聚体的检测结果分析[J].分子诊断与治疗杂志,2009,1(2):108-110. 被引量:5
  • 2陈智伟,廖美琳.RECIST标准在肿瘤治疗疗效评价中的应用[J].中国肿瘤,2004,13(10):616-618. 被引量:176
  • 3Marinho FC,Takagaki TY. Hypercoagulability and lung cancer [ J].J Bras Pneumol,2008 ,34(5) :312 -322.
  • 4Unsal E,Atalay F, Atikcan S,et al. Prognostic significance of he -mostatic parameters in patients with lung cancer[ J]. Respir Med,2004,98(2) :93 -98.
  • 5Koh SC,Razvi K,Chan YH,et al. The association with age,humantissue kallikreins6 and 10 and hemostatic markers for survival out -come from epithelial ovarian cancer [ J] . Arch Gynecol Obstet,2011,284(1) :183 -190.
  • 6Blackwell K,Hurwitz H,Liebermang,et al. Circu lating D2dimerlevels are better predictors of overall survival and disease progres-sion than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma [J]. Cancer,2004,101(1) :77282.
  • 7Altiay G,Ciftci A, Demir M,et al. High plasma D - dimer level is as-sociated with decreased survial in patients with lung cancer[J]. ClinOncol(R Coll Radiol) ,2007,19(7) :494 -498.
  • 8田同德,陈信义,储真真.恶性肿瘤血液高凝状态与中医血瘀证关系探讨及其防治对策[C].第三届国际中医、中西医结合肿瘤学术交流大会暨第十二届全国中西医结合肿瘤学术大会论文汇编,2010:532 -533.
  • 9Zurborn KH,Duscha H,Gram J, et al.Investigations of coagulation system and fibrinolysis in patients with disseminated adenocarcinomas and non-Hodgkin lymphomas[].Oncology.1990
  • 10于书云,郭笑冬.肺癌复发与凝血变化的相关性的临床观察[J].医学理论与实践,2008,21(9):1041-1042. 被引量:2

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部