绞股蓝与包醛氧淀粉治疗慢性肾功能衰竭临床研究

Cliulcal research of treatment of chronic renal failure by Gynostemma pentaphyllum makino and oxyamyli aldehydum tectum

目的探讨中西医结合治疗慢性肾功能衰竭（CRF）的疗效。方法98例（CRF）患者随机分成中西医结合组（治疗组）49例与西医经（对照组）49例，对照组行包醛氧淀粉治疗，治疗组采用纯中药制剂绞股蓝与西医包醛氧淀粉联合治疗。疗程均为3个月。结果治疗组显效率和总有效率分别为22．45％、67.35％，显著高于对照组的10．20％、38．78％（P＜0．05），治疗组转化为终末期肾病发生率和不良反应发生率分别为20．00％、18．37％，显著低于对照组的50．00％、42．86％（P＜0．05）。结论绞股蓝与包醛氧淀粉组成的中西医结合疗法优于单纯西医治疗。

Object:To explore the results of chronic renal failure treated by integrated Chinese - Westem therapy. Methods: 98 cases of patients CRF were randomized to the integratd Chinese - Western therapy group(therapeutic group)49 cases and the western therapy group(contral group)49 cases. The control group were treated by Oxyamyli aldehydum tectum, while the therapeutic group were treated by the combined method of medicinal Gynostemma pentaphyllum makino and Oxyamyli aldehydum tectum. Both courses of treatment were three months. Results: The notable effective rate and total effective rate were 22 .45 % and 67. 35 % respectively in the therapeutic group, significantly higher than those (10 .20% and 38 .78 % ) of control goup)P < 0 .05). The occurrence rate of turing into end stage renal disease (ESRD)and adverse reactions were 20.00% and 18. 37%, significanily lower than those (50.00% and 42. 86% ) of control group (P < 0 .05) Conclusion The integrated Chinese - Western therapy of Gyonstemma Pentaphyllum makino and Oxyamyli aldehydum tectum was sliPerior than pure western therapy.