摘要
应用金标抗人ＩｇＧ４ ＭｃＡｂ 浸测试验检测１７３ 例脑囊虫病患者血清中特异ＩｇＧ４，并与其脑ＣＴ、ＭＲ影像分型进行对比分析。结果显示，脑囊虫病患者血清中特异ＩｇＧ４ 的阳性率和阳性强度与囊尾蚴在脑组织内寄生的数量，以及存活、崩解、死亡、钙化等病理变化相一致，可客观地反映脑组织内囊虫感染状态。检测患者血清中特异ＩｇＧ４ 可用于脑囊虫病早期诊断、疗效考核以及对疾病状态的评价。
The results of detection of specific IgG4 in sera of 173 cerebral cysticercosis patients by dip test using gold labeled anti human IgG4 monoclonal antibody(McAb) were reported and compared with the case CT and MR scans. The positive rate and intensity of the specific IgG4 in sera of cerebral cysticercosis patients are coincident with the amount and status (living, disintegration, death, calcification and so on) of the cysticercus parasitized in the brain tissue of patients, and can reveal the infectious status of cysticercus in the brain. Therefore, testing of specific IgG4 in sera of patients can be used for early diagnosis, treatment efficiency evaluation and status assessment of cerebral cysticercosis.
出处
《中国寄生虫病防治杂志》
CSCD
1999年第4期269-271,共3页
Chinese Journal of Parasitic Disease Control
关键词
脑囊虫病
IGG4
CT
诊断
NMR
Cerebral cysticercosis, IgG4, CT, MR, diagnosis, treatment efficiency evaluation
