小儿肺炎血清降钙素原检测的临床意义

The clinical significance of serum procalcitonin detection in children with pneumonia

目的探讨血清降钙素原检测在小儿肺炎患儿中的临床意义,为临床抗生素的合理使用提供依据。方法 60例肺炎患儿,其中细菌性肺炎32例,病毒性肺炎28例,采用化学发光免疫法测定患儿血清降钙素原含量。结果细菌性肺炎组患儿血清降钙素原含量为(2.69±0.63)μg/L,而病毒性肺炎组患儿血清降钙素原含量为(0.36±0.12)μg/L,细菌性肺炎组患儿血清降钙素原水平明显高于病毒性肺炎组,差异有统计学意义(P<0.01)。结论 血清降钙素原测定有助于小儿肺炎诊断及鉴别诊断,可作为临床抗生素的使用依据。

Objective To explore the clinical significance of serum procalcitonin detection in children with pneumonia,and provide evidence for clinical use of antibiotics.Methods A total of 60 children with pneumonia were divided into bacterial neumonia group（n=32） and viral neumonia group（n=28）,and serum procalcitonin was determined by chemiluminescence immunoassay.Results The serum level of procalcitonin in the bacterial neumonia group was（2.69±0.63）μg/L and the viral neumonia was（0.36±0.12）μg/L,The serum level of procalcitonin was more elevated in bacterial neumonia group than that of viral neumonia group,and the difference was statistically significant（P0.01）.Conclusion Serum procalcitonin contributes to diagnosis and differential diagnosis of pneumonia in children,which may provide basis for clinical use of antibiotics.