四川成都地区2型单纯疱疹病毒检测结果分析

Analysis on the test result of patients with herpes simplex virus type 2 in Chengdu Sichuan

目的了解四川成都地区疑有单纯疱疹病毒2型(HSV-2)感染患者的感染情况。方法用荧光定量(FQ-PCR)法对1 107例疑有HSV-2感染的门诊患者进行检测。结果 (1)1 107例生殖器疱疹疑似患者检测HSV-2阳性患者616例,阳性率为55.65%(616/1107),其中男性患者阳性率47.58%(59/124),女性患者阳性率56.66%(557/983),男性患者与女性患者的发病率比较,差异具有统计学意义(P<0.05)。(2)三个年龄段患者,即≤20岁,>20岁～≤40岁,>40岁的阳性率分别为60.34%(70/116)、55.23%(486/880)、54.05%(60/111),三个年龄段患者发病率比较,差异不具有统计学意义(P>0.05)。结论 (1)成都地区生殖器疱疹疑似患者中HSV-2感染率高,感染率有性别差异,女性发病率高于男性。(2)不同年龄段发病率差异不具有统计学意义。(3)FQ-PCR具有快速,简便,灵敏度高等优点,适用于临床检测。

Objective To investigate the prevalence of patients with suspected herpes simplex virus type 2（HSV-2） visited a sexually transmitted diseases clinic.Methods Fluorescence quantitative polymerase reaction technology（FQ-PCR） was used to detect HSV-2 in 1 107 patients with suspected genital herpes（GH）.Results（1）Among 1 107 patients,HSV-2 positive was found in 616 patients（55.65%）.The positive detection rates of HSV-2 in male and female patients were 47.58%,56.66%.There was significant difference of the positive detection rate between male and female（P0.05）.（2）The positive detection rates of three age groups,including age ≤20,20-40,40,were 60.34%（70/116）,55.23%（486/880）,54.05%（60/111）,respectively.There was no statistical significance in the three groups（P0.05）.Conclusion（1）There is a high infection rate of HSV-2 in the area.There is a significant difference of positive detection rate between male and female.The incidence rate in female is higher than that in male.（2）There is no difference of the positive detection rate in different age groups.（3）FQ-PCR is a rapid,easy,sensitive and special assay to detect HSV,and it can be applied for clinical diagnosis.