重型颅脑损伤并发应激性溃疡出血的治疗

Therapy of Severe Craniocerebral Injury Patients Complicated with Stress Ulcer Bleeding

目的探讨重型颅脑损伤术后采用生大黄剂灌注方法对治疗并发应激溃疡出血的效果。方法 71例重型颅脑损伤患者开颅手术,入选53例术后消化道应激性溃疡出血的患者分研究组和对照组进行治疗比对;研究组行生大黄剂鼻饲灌注及护理,对照组行常规脱水、亚低温、抗炎、机械通气等常规性治疗方法。结果治疗组总有效率达到,而对照组仅为;研究组显效率、总有效率均优于对照组。两组数据经统计学分析具有显著差异(P<0.05)。结论运用生大黄粉制成灌注制剂对治疗重型颅脑损伤并发应激性溃疡出血患者具有较显著疗效,同时大黄也具有消除脑水肿、改善患者脑部缺血状态等作用。

Objective Discuss the effects of Rheum palmatum perfusion on treatment of complicated stress ulcer bleeding after operation of severe craniocerebral injury.Method 71 patients of severe craniocerebral injury were done with craniotomy.53 of them with stress ulcer bleeding in digestive tract were divided into the research group and control group for comparison.The research group was provided with Rheum palmatum perfusion and nursing.The control group was provided with conventional therapy such as conventional dehydration,subhypothermia,anti-inflammation and mechanical ventilation.Result Total effective rate of research group reached,but that of the control group only reached.Both marked improvement rate and total effective rate of the research group are superior to those of the control group.Data of the two groups showed significant difference through statistical analysis（P〈0.05）.Conclusion Rheum palmatum perfusion preparation made of its powder proves to be of significant curative effects on severe craniocerebral injury patients complicated with stress ulcer bleeding.Meanwhile it may cure hydrocephalus and improve cerebral ischemia,which is favorable for recovery of brain tissue injury and autonomic nervous function.