护理干预在退白汤联合NB—UVB紫外线照射治疗寻常型白癜风中的应用

Application of nursing intervention for treating vitiligo vulgaris by Anti-Vitiligo Decoction associated with NB-UVB irradiation

目的探讨护理干预在退白汤联合NB-UVB紫外线照射治疗寻常型白癜风中的应用效果。方法将178例寻常型白癜风患者按就诊顺序采用单双号抽签法分为实验组89例和对照组89例；实验组内服退白汤联合NB-UVB紫外线照射，同时配合适当的护理于预；对照组仅内服退白汤联合NB—UVB紫外线照射，两组患者疗程均为3个月。采用统一的疗效评定标准进行疗效和安全性评价。结果实验组有效率75．28％，对照组有效率为60．67％，两组比较差异有统计学意义（χ^2=4．3616，P〈0．05）；实验组治疗寻常型白癜风局限性疗效明显优于治疗散发性疗效，差异有统计学意义（85．42％比63．41％，χ^2=5．7523，P〈0．05）；两组患者总不良反应发生率比较，差异无统计学意义（χ^2=0．0465，P〉0．05）。结论退白汤内服联合NB-UVB紫外线照射并配合适当的护理干预是治疗寻常型白癜风的有效方法。

Objective To investigate the clinical effect of nursing intervention for treating vitiligo vulgaris by Anti-Vitiligo Decoction associated with NB-UVB irradiation. Methods 178 patients with vitiligo vulgaris were divided into two groups according to the treatment sequence balloting with odd and even numbers. 89 patients in treating group and 89 patients in control group took Anfi-Vitiligo Decoction associated with NB-UVB irradiation, besides that patients in treating group received the appropriated nursing intervention. The effectiveness and safety were appreciated by the standard of PASI. Results The effect ratio of the two groups were 75.28% and 60. 67% respectively, and there was statistically significant difference between the two groups （ χ^2 = 4. 361 6, P 〈 0. 05 ）. In treating group, the effect of treating limited vitiligo vulgaris was significantly better than treating the scattered vitiligo vulgaris （ 85.42% vs 63.41%, χ^2 = 5. 752 3, P 〈 0. 05 ）. The incidence of side effects was similar in the two groups （ χ^2 = 0. 046 5, P 〉 0. 05 ）. Conclusions It is a effective method to treat vitiligo vulgaris by using Anti-Vitiligo Decoction associated with NB-UVB irradiation and appropriated nursing intervention.