氟达拉滨化疗后继发单纯红细胞再生障碍性贫血三例并文献复习
被引量:4
摘要
目的研究氟达拉滨继发单纯红细胞再生障碍性贫血(PRCA)的临床特点及治疗方法。方法回顾分析3例氟达拉滨继发PRCA病例资料,并复习相关文献。结果3例在化疗后1~6个疗程出现PRCA,需要输血治疗,并需要停止原发病的治疗。结论氟达拉滨继发PRCA,一旦出现,通常治疗困难,并会延误原发病的治疗。目前有用利妥昔单抗治疗成功的报道。氟达拉滨导致PRCA的机制目前还不清楚,需要进一步研究。
出处
《白血病.淋巴瘤》
CAS
2011年第7期430-432,共3页
Journal of Leukemia & Lymphoma
参考文献10
-
1邓秀芝,王毅力,高健.以氟达拉滨为主的联合方案治疗慢性淋巴细胞增殖性疾病10例[J].白血病.淋巴瘤,2010,19(9):562-564. 被引量:2
-
2Djaidetti M, Blay A, Bergman M, et al. Pure red cell aplasia-a rare disease with multiple causes. Biomed Pharmacother, 2003, 57: 326- 332.
-
3Hirokaw M, Sawada K, Fujishima N, et al. Acquired pure red cell aplasia associated with malignant lymphomas: a nationwide cohort study in Japan for the PRCA Collaborative Study Group. Am J Hematol, 2009, 84: 144-148.
-
4Leporrier M, Reman O, Troussard X. Pure red-cell aplasia with fludarabine for chronic lymphocytic leukaemia. Lancet, 1993, 342: 555.
-
5Johnson S, Smith AG, Loffler H, et al. Muhicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL. Lancet, 1996, 347: 1432-1438.
-
6Ha.ssan G. Successful treatment of pure red cell aplasia with rituximab in patients with chronic lymphocytic leukemia. Blood, 2002, 99:1092-1094.
-
7VeeIken H, Wasch R, Behringer D, et al. Pure red ceil aplasia after allogeneic stem cell transplantation with reduced conditioning. Bone Marrow Transplant, 2000, 26:911-915.
-
8Fujiwara T, Yamada M, Miyamura K, et al. Fludarabine- and cyclophosphamide-based nonmyeloablative conditioning regimen for transplantation of chronic granulomatous disease: possible correlation with prolonged pure red cell ap|asia. Int J Hematol, 2004, 79: 293-297.
-
9Gautam B, Susan O, William G, et al. Immune anaemias in patients with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab-incidence and predictors. Bri J Haematol, 2007, 136: 800-805.
-
10Au WY, Lain CC, Chim CS, et al. Alemtuzumab induced complete remission of therapy-resistant pure red cell aplasia. Leuk Res, 2005, 29: 1213-1215.
二级参考文献9
-
1Reed DN Jr,Vitale GC,Martin R,et al.Bileduct carcinoma:trends in treatment in the nineties.Am Surg,2000,66:711-714.
-
2Grever MR,Kopecky,Coltman CA,et al.Fludarabine monophosphate:a potentially useful agent in chronic lymphocytic leukemia.Nouv Rev Fr Hemutol,1988,30:451-459.
-
3O'Brien S,Kantarjian H,Beran M,et al.Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis derived prognostic model for response to treatment.Blood,1993,82:1695-1700.
-
4Adkins JC,Peters Dn,Markham A.Fludarabine An update of its pharmacology and use in the treatment of haematological malignancies.Drugs,1997,53:1005-1037.
-
5Keating MJ,O'Briens,Lerners,et al.Long term followup of patients with chronic lymphocytic leukemia (CLL) receiving fludarabine regimens as initial therapy.Blood,1998,92:1165-1171.
-
6Bellosillo B,Villamor N,Colomer D,et al.In vitro evolution of fludarabine in combination with cyclophosphamide and /or mitoxantrone in B-cell chronic lymphocytic leukemia.Blood,1999,94:2836-2843.
-
7Aksoy S,Abali H,Kilickap S,et al.Fludarabine phosphate may be useful in the treatment of graft-Versus-host disease.Med Hypotheses,2005,64:1150-1152.
-
8吕书晴,王健民,宋献民,陈莉,许晓倩,章卫平,侯军,邱慧颖,黄崇媚,杨建民.含氟达拉滨的联合化疗方案治疗慢性淋巴细胞白血病/小淋巴细胞性淋巴瘤[J].临床肿瘤学杂志,2008,13(2):119-122. 被引量:4
-
9钱林生,郝长来.慢性淋巴细胞增殖性疾病及其分类[J].中国实用内科杂志,2001,21(6):321-323. 被引量:3
同被引文献20
-
1井丽萍,邵宗鸿.获得性纯红细胞再生障碍发病机制及治疗[J].中华血液学杂志,2004,25(8):510-512. 被引量:7
-
2张学美,李惠民,聂波,温柏平,谢喻,杨绵本.11例纯红细胞再生障碍性贫血的临床分析[J].临床血液学杂志,2006,19(4):238-239. 被引量:5
-
3刘敏,刘霆,孟文彤,朱焕玲,崔旭.γδΤ细胞在获得性纯红细胞再生障碍性贫血发病机制中的作用[J].中国实验血液学杂志,2007,15(1):142-146. 被引量:5
-
4Fujiao S, Tsuda H. Th1/Th2 balance alteration in the clinical course of a patient with pure red cell aplasia and thymoma[J]. Br J Haematol, 1998, 103(2):308-310.
-
5Masuda M, Teramura M, Mastsuda A,et al. Clonal T cells of pure red cell aplasia[J]. Am J Hematol, 2005, 79(4): 332-333.
-
6Shin S, Kim AH, Park J,et al. Analysis of immunoglobulin and T cell receptor gene rearrangement in the bone marrow of lymphoid neoplasia using BIOMED-2 multiplex polymerase chain reaction [J]. Int J Med Sci, 2013, 10(11):1510-1517. DOI: 10. 7150/ijms. 5342.
-
7Fujishima N, Hirokawa M, Fujishirna M, et al. Oligoclonal T cell expansion in blood but not ia the thymus from a patient with thymoma-associated pure red cell aplasia [J]. Haematologica, 2006, 91(12 Suppl) :ECR47.
-
8Guang-sheng He Xiang Zhang De-pei Wu Ai-ning Sun Miao Miao Xiu-li Wang Zheng-ming Jin.RETREATMENT WITH FLUDARABINE AND CYCLOSPORINE FOR ONE CASE OF REFRACTORY PURE RED CELL APLASIA[J].Chinese Medical Sciences Journal,2008,23(1):60-62. 被引量:3
-
9王爱清,耿美菊,朱明清,陈黎.纯红细胞再生障碍性贫血患者外周血淋巴细胞表型及活化指标分析[J].苏州大学学报(医学版),2008,28(2):292-293. 被引量:7
-
10张静楠,郭晓楠,徐世荣.纯红细胞再生障碍性贫血的研究进展[J].诊断学理论与实践,2010,9(3):280-284. 被引量:14
引证文献4
-
1李国栋,成志勇,梁丽青,刘玉梅,刘倩,王丽荣,张丽丽.高三尖杉酯碱联合依托泊苷致急性髓系白血病化疗后长期骨髓抑制1例[J].南昌大学学报(医学版),2014,54(12):92-92. 被引量:1
-
2王增胜,黄琴,刘虹,富玲,王晓敏.获得性纯红细胞再生障碍患者淋巴细胞亚群特点及环孢素对其影响的研究[J].肿瘤研究与临床,2015,27(8):526-528. 被引量:3
-
3王增胜,安利,木舍塔拜尔,张晓燕,富玲,王晓敏.克隆性TCR基因重排在获得性纯红细胞再生障碍性贫血的意义[J].中华医学遗传学杂志,2016,33(3):369-372. 被引量:2
-
4赵志强,李香丽,张宗,王列样.滤泡淋巴瘤氟达拉滨治疗后继发再生障碍性贫血一例并文献复习[J].白血病.淋巴瘤,2019,28(3):174-176. 被引量:1
二级引证文献7
-
1范春梅.流式细胞术在恶性肿瘤患者外周血T细胞亚群检测中应用分析[J].中国卫生标准管理,2015,6(31):151-152. 被引量:4
-
2王增胜,安利,木舍塔拜尔,张晓燕,富玲,王晓敏.克隆性TCR基因重排在获得性纯红细胞再生障碍性贫血的意义[J].中华医学遗传学杂志,2016,33(3):369-372. 被引量:2
-
3朱琳,安利,王增胜,富玲.获得性纯红细胞再生障碍性贫血患者的T淋巴细胞亚群分析及疗效观察[J].国际输血及血液学杂志,2016,39(4):319-324. 被引量:7
-
4王英慧,赵晶,王雯欣,董霞,史恩红.获得性纯红细胞再生障碍性贫血10例报告并文献复习[J].临床血液学杂志,2017,30(4):554-556. 被引量:2
-
5龚明.三氧化二砷联合环孢素治疗再生障碍性贫血的临床观察[J].北方药学,2020,17(5):104-105.
-
6王丽丽,韩明明.促红细胞生成素联合环孢素A治疗老年获得性纯红细胞再生障碍性贫血的疗效及相关机制[J].检验医学与临床,2021,18(10):1462-1464. 被引量:6
-
7徐燕,叶利锋,高鳌.R-CHOP治疗与R-DAEPOCH方案治疗弥漫大B细胞淋巴瘤的近期疗效和毒副作用比较[J].当代医学,2024,30(12):171-174.
-
1陆兆炯.纯红细胞再生障碍性贫血、胸腺瘤漏诊1例[J].右江民族医学院学报,2007,29(2):222-222.
-
2沈丽芳,莫伟明,陈琴琴.“四片联检”形态学诊断单纯红细胞再生障碍性贫血一例伴文献复习[J].中国医师杂志,2015,17(8):1273-1274.
-
3刘录恒.纯红细胞再生障碍性贫血1例诊断分析[J].检验医学与临床,2008,5(8):492-493.
-
4施兵,黄晓军.利奈唑胺致异基因造血干细胞移植后纯红细胞再生障碍性贫血一例报告并文献复习[J].医学临床研究,2015,32(4):774-776. 被引量:1
-
5陈冬梅,邱方芳,马莉.继发于胸腺瘤的单纯红细胞再生障碍性贫血1例报告[J].新医学,2002,33(1):40-40. 被引量:1
-
6续瑞芳,金春权,郭在晨.儿童慢性淋巴细胞性甲状腺炎合并单纯红细胞再生障碍性贫血一例[J].中华儿科杂志,1997,35(9):457-457.
-
7蔡宝松,张彦匣.胸腺瘤合并单纯红细胞再生障碍性贫血1例[J].现代中西医结合杂志,2012,21(15):1624-1624. 被引量:1
-
8罗辉遇,陈梓宏,余忠华.胸腺瘤伴单纯红细胞再生障碍性贫血的研究概况(附1例报告)[J].临床荟萃,1999,14(12):548-549. 被引量:4
-
9高宝成.氯霉素引起单纯红细胞再生障碍性贫血一例报告[J].吉林医学情报,1992(4):51-52.
-
10王晓英.大剂量丙种球蛋白与雄性激素联合治疗重型再生障碍性贫血[J].中国基层医药,2003,10(3):233-234. 被引量:1