美常安治疗肠易激综合征临床效果评价

Live Combined Bacillus Subtilis and Enterococcus Faecium Enteric-coated Capsules in the treatment of irritable bowel syndrome

目的:探讨美常安治疗肠易激综合征(IBS)的临床疗效。方法:对IBS患者98例分为两组,对照组给予常规对症治疗,观察组在对照组治疗基础上增加美常安口服,干预周期为4周,实验期间患者不接受其他治疗。分别于实验开始、治疗2周、4周以及停药后2周对两组患者进行症状评分,比较治疗前后的症状、临床疗效及体征。结果:观察组经美常安治疗后总症状缓解明显,治疗总缓解率在50%以上,停药后2周效果稳定;IBS患者大便紧迫感、腹部疼痛和排便频率症状缓解明显;枯草杆菌和屎肠球菌数量增加,与对照组比较有显著性差异。结论:益生菌制剂美常安可以显著改善IBS症状,具有明显的治疗效果。

Objective：To evaluate Live Combined Bacillus Subtilis and Enterococcus Faecium Entericcoated Capsules in the treatment of irritable bowel syndrome （IBS）. Methods： 98 cases of IBS patients were divided into two groups. The control group were given routine symptomatic treatment, the observed group increased Live Combined Bacillus Subtilis and Enterococcus Faecium Entericcoated Capsules. The intervention period is 4 weeks, with no other treatment. The symptoms, clinical efficacy and signs were observed before and after the treatment. Results：In live Combined Bacillus Subtilis and Enterococcus Faecium Enteric-coated Capsules treatment group, the total symptoms were relieved significantly. The total effective rate was 50%,with two weeks of relatively stable; IBS patients with abdominal pain, fecal urgency and stool frequency symptoms were improved significance; Laetobacillus and Bifidobacterium increased, the change was significant difference. Conclusion：The probiotics Live Combined Bacillus Subtilis and Enterococeus Faecium Enter- ic-coated Capsules can effectively improve the clinical symptoms of patients with IBS and increase the therapeutic effects.