燕麦对高胆固醇血症男性中老年人血脂水平的影响

Effect of Oat on Blood Lipids Level of Middle-aged and Elderly Men with hyPercholesterolemia

目的:观察食用燕麦对城市患高胆固醇血症男性中、老年人空腹血脂水平的影响。方法:参考《中国成人血脂异常防治指南》中的判断标准,将65名患高胆固醇血症男性中、老年人随机分为2组,分别为燕麦组(33人),每人每日给予100g即冲即食燕麦片;对照组(32人),每人每日给予100g普通挂面,试验周期6周。研究开始前和6周时对两组受试者进行基本健康状况问卷调查、人体测量、血生化检测以及膳食调查。结果:燕麦组和对照组的能量、蛋白质、脂肪、碳水化合物摄入量无显著差异,但燕麦组膳食纤维摄入量明显增加,增幅显著大于对照组,P<0.05。6周结束时,燕麦组血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白B(apoB)水平显著降低(P<0.05);血清TC、LDL-C平均降低幅度分别为7.0%和7.5%。对照组血清胆固醇、脂蛋白及载脂蛋白水平在试验期间未见显著变化。结论:对于我国城市中患高胆固醇血症的男性中、老年人,每日食用一定量的燕麦作为膳食中的粮谷类食物,可有效降低血清TC、LDL-C和apoB水平,减少心脑血管疾病发生的危险。

Objective：To observe the impact of oat intake on the blood lipid level of middle-aged and elderly men with hypercholesterolemia. Methods：By referring to the standards in the Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults,65 middle-aged and elderly men with hypercholesterolemia was selected and randomly assigned to consume 100 grams of instant oatmeal per day（Oat group,33 subjects） or receive 100 grams common noodle（Control,32 subjects） for 6 weeks. At the beginning and the final time of the intervention,basic health condition questionnaire survey,body measurement,blood biochemical testing and diet survey were undertaken. Results：There is no significant changes in energy,protein,fat,carbohydrate intake between the two groups while dietary fiber intake significantly increased within Oat group（P0.05） . Oat diet resulted in a significant reduction in serum TC,LDL-C,and Apo B（P0.05） and the average percentage of TC,LDL-C reduction reached 7.0%,7.5% in oat group. There is no significant change in blood lipids level in Control group. Conclusion：For urban male elderly residents,inclusion oat,a kind of whole grain foods,as part of the diet can effectively lower serum total,LDC cholesterol and apo B level and thus reduce cardiovascular disease risk in urban middle-aged and elderly men.