IgA肾病临床与病理分型

Clinical and pathological analysis of IgA nephropathy

目的探讨原发性IgA肾病的病理与临床疗效及预后之间的关系。方法对55例原发性IgA肾病的患者进行肾穿刺后分析其病理分型、临床表现、疗效及预后。结果病理分型轻者多表现为无症状血尿和／或蛋白尿，疗效较好，而病理分型重者临床表现多为肾病综合征伴高血压、肾功能不全，疗效差，预后差，提示病理分型与临床表现、疗效及预后有明显相关。结论早期肾穿刺活检及早治疗，可以延缓肾功能衰竭进展。

Objective To study the pathology of primary IgA nephropathy and its clinical characteristics and explore the relationship between efficacy and prognosis. Methods Fifty - five patients with primary IgA nephropathy had their renal biopsy and analysis was done of pathological type, clinical manifestations, efficacy and prognosis. Results Patients with mild hematuria and/or proteinuria had good efficacy, patients with severe pathological types of asymptomatic pathological types of severe nephrotic syndrome with hypertension and renal insufficiency had poor efficacy. It indicated that renal pathology was significantly related to clinical manifestations, efficacy and prognosis. Conclusions Early renal biopsy and treatment can delay the deterioration of renal failure.