脾动脉栓塞治疗慢性特发性血小板减少性紫癜

Splenic artery embolism in the treatment of chronic idiopathic thrombocytopenic purpura

目的探讨脾动脉栓塞治疗特发性血小板减少性紫癜的临床疗效。方法选择102例药物治疗无效的特发性血小板减少性紫癜患者在数字减影血管造影（DSA）下行超选择性脾动脉栓塞术治疗，栓塞面积约81％左右，并于术后定时复查血常规，观察其疗效。结果全部患者在第3天血小板开始上升，7—14d达高峰，即时性疗效为99例（97．1％），近期疗效为80例（78．4％），0．5年以上的远期疗效为66．8％。结论部分脾动脉栓塞术治疗特发性血小板减少性紫癜疗效明显，并发症少，具有重要临床价值，值得推广。

Objective To explore the clinical effect of partial splenic embolization in the treatment of idiopathic thrombocytopenic purpura（ITP）. Methods One hundred and two cases who were diagnosed as ITP failed by medicine therapy were done by selective splenic artery embolism in digital subtraction angiography. The embolization area of splenic artery was about 81%. The blood routine examination was performed regularly and the effect of treatment was evaluated. Results All of their platelet began to rise on the postoperative third day and reached the top during the 7 - 14 days. The instant effect for 99 cases （97.1%）, and the short term curative effect fo/80 cases （78.4%）. The long term effect aboved half one year was 66. 8%. Conclusions It is showed that the effect of partial splenic artery embolism therapy is obvious on ITP with few complication, is worthy of promotion.