摘要
目的比较食管癌手术麻醉中单肺通气(OLV)期间采用不同潮气量容量控制通气对血流动力学、气道压力以及动脉血气的影响。方法选择50例择期行食管癌根治术成年患者,ASAⅠ~Ⅱ级,随机分为两组,A组(低潮气量高频率)和B组(正常潮气量频率)。A组单肺通气时潮气量(VT)6ml/kg,呼吸频率18次/min,B组单肺通气时潮气量(VT)10ml/kg,呼吸频率12次/min。比较两组各时段的血流动力学、气道峰压(Ppeak)、动脉血氧分压(PaO2)。结果两组各时段血流动力学无统计学意义(P>0.05),两组气道峰压(Ppeak)在OLV时差异有统计学意义(P<0.05),两组PaO2差异有统计学意义(P<0.05)。结论食管癌根治术OLV期间采用低潮气量高频率通气模式在降低气道压力,增加动脉血氧分压等方面优于正常潮气量频率通气模式。
Objective To compare the impacts of different tidal volume of volume-controlled ventilation(VCV) on hemodynamic state,airway pressures,and arterial oxygenation during one-lung ventilation(OLV) for esophageal cancer radical operation.Methods Totally 50 ASA I~Ⅱadult patients undergoing esophageal cancer radical operation,were randomized equally into 2 groups:group A(low tidal volume with high respiratory rate) and group B(normal tidal volume with normal respiratory rate) .after anesthetic induction,the patients received two-lung ventilation followed by one-long ventilation.During one-long ventilation,the patients of group A received tidal volume 6ml/kg and respiratory rate 18/min,the patients of group B received tidal volume 10ml/kg and respiratory rate 12/min.Hemodynamics,peak airway pressure(Ppeak) ,PaO2,and were determined at different time points in both groups.Results Hemodynamic indices did not differ significantly between the two groups(P0.05) .the Ppeak of group A was lower than that of group B significantly(P0.05) ,the PaO2 of group A was higher than that of group B significantly(P0.05) .Conclusions During OLV for esophageal cancer radical operation,low tidal volume with high respiratory rate is superior to normal tidal volume with normal respiratory rate in lowering airway pressure and increasing PaO2.
出处
《医药论坛杂志》
2011年第10期93-95,共3页
Journal of Medical Forum
关键词
肺通气
容量控制通气
单肺通气
低潮气量
Pulmonary ventilation
Volume controlled
One-lung ventilation
Low tidal volume