聚天冬氨酸修饰玻碳电极伏安法检测阿魏酸

Voltammetric Determination of Ferulic Acid Using a GC Electrode Modified with Poly-aspartic Acid Film

通过在水溶液中直接电聚合的方法制备了聚天冬氨酸修饰玻碳电极.在pH为4.5,0.1 mol.L-1HAc-NaAc缓冲溶液中,修饰电极对阿魏酸表现出良好的吸附能力,显著地提高了阿魏酸的电信号强度.探讨了聚天冬氨酸修饰玻碳电极的作用机理,建立了阿魏酸的快速检测方法.在浓度为9.1×10-7～3.0×10-3mol.L-1范围内,阿魏酸的微分脉冲氧化峰电流与其浓度呈线性关系,检出限为3.1×10-7mol.L-1.此方法用于中成药逍遥丸中痕量阿魏酸的检测,回收率为97.9%～102.2%.

A novel electrochemical sensor was prepared by direct electro-polymerization of DL-aspartic acid on the surface of glassy carbon electrode in aqueous media. In pH 4.5, 0. 1 mol · L-1 HAc-NaAc buffer solution, the film modified electrode exhibited excellent adsorption capacity to ferulic acid and improved the electrochemical responses significantly. The action mechanism of modified electrode was preliminarily explored,and a fast analytical method for ferulic acid was established. In the range of 9.1 ×10^-7 to 3.0 ×10^- 3 mol · L ^-1, the differential pulse voltammetric peak current had a linear relationship to the concentration, and the detection limit was estimated to be 3.1 ×10^- 7 mol · L^- 1. Thismethod was adopted to detect the trace amount of ferulic acid in Chinese patent medicine of Xiaoyao Pills, and the recovery was from 97.9% to 102.2%.