摘要
目的探讨131碘(131I)对甲亢性心脏病(甲亢心)患者的一氧化氮(NO)和内皮素(ET)水平的影响。方法用131I治疗甲亢心患者36例,分别观察治疗前后血NO和ET水平,并与对照组进行比较。结果 131I治疗前,甲亢心组患者血NO和ET水平与正常对照组比较显著增高(P<0.01),131I治疗3个月后,甲亢心组患者血NO、ET水平较治疗前均显著下降(P<0.01)。结论 131I用于甲亢心的治疗能够显著降低NO和ET水平,改善预后。
Objective To study the effect of 131I on nitric oxide（NO） and endothelin（ET） levels in patients With hyperthyroid heart disease.Methods 36 cases of hyperthyroid heart disease were treated with 131I（the study group）.The serum concentrations of NO and ET were observed and compared with that of the subjects in the control group（n=30）.Results Before treatment,the serum concentrations of NO and ET levels in the study group were significantly higher than that in the control group.The levels decreased significantly 3 months after treatment（P0.01）.Conclusion 131I had the effects of decreasing the serum concentrations of NO and ET in patients with hyperthyroid heart disease.
出处
《海南医学》
CAS
2011年第15期35-36,共2页
Hainan Medical Journal
