双歧杆菌乳杆菌三联活菌辅助治疗婴儿变应特异性皮炎的临床观察

Obseration of effects of live combined bifidobacterium and lactobacillus tablets on adjuvant treatment of infant's Atopic dermatitis

目的探讨双歧杆菌乳杆菌三联活菌片辅助治疗婴儿变应特异性皮炎的效果。方法选择101例出生0～6个月患变应特异性皮炎的婴儿,随机将其分为两组,对照组43例给予莫匹罗星软膏外涂患处,每日早晚各1次;治疗组58例,在以上外涂的基础上给予口服双歧杆菌乳杆菌三联活菌片剂,每日3次,每次2片。分别在就诊第1天和第7天疗程结束时评估临床症状体征及疗效。结果对照组与治疗组有效率分别为53.5%和91.4%,差异具有统计学意义(P<0.01)。结论双歧杆菌乳杆菌三联活菌片剂辅助治疗婴儿变应特异性皮炎有明显疗效,值得推广。

Objective To explore the therapeutic effects of live combined bifidobacterium and lactobacillus tablets on infant＇s atopic dermatitis.Methods 101 cases of atopic dermatitis in infants were randomly classified into two groups,the 43 patients In control were given the mupirocin ointment liniment twice a day;on the basis of above extemal treatment for the 53 patients in treatment group was used live combined bifidobacterium and lactobacillus tablets third a day.The the rapeutic effects was evaluated at the 1st day and 7th day after treatment.Results The effect rate of control group was 53.4%and 91.3% in treatment group.There were significant difference between twe group s（P0.01）.Conclusion The CombinedBifidobacterium and Lactobacillus Tablets has remarkable thempeutic effects on adjutant treatment of infant＇s atopic dermatitis.It is worth applyingextensively in clinical practice.