中草药还原法制备银纳米颗粒及其抗菌性能

Biosynthesis of Silver Nanoparticles from Various Medicinal Plant Extracts and Their Antibacterial Properties

分别以中草药丁香、山茱萸、地榆和乌梅的提取液为还原剂和保护剂合成银纳米颗粒,利用紫外-可见吸收光谱(UV-vis)、透射电镜(TEM)以及X射线粉末衍射(XRD)对产物进行了表征。结果表明,所得银纳米颗粒呈近球形,提高提取液的pH有利于获得粒径较小、分散性好、稳定性高的银纳米颗粒。进一步考察制得的银纳米颗粒的抗菌性能,结果表明,其对大肠杆菌和金黄色葡萄球菌有很强的抑制作用,最小抑菌质量浓度(M IC)分别可达1.69和3.38 mg/L。

Quasi-spherical silver nanoparticles（AgNPs） were synthesized from the extracts of different medicinal plants including Syzygium aromaticum,Cornus officinalis,Prunus mume and Sanguisorba officinalis,and were subsequently characterized by means of UV-visible spectroscopy,transmission electron microscopy and X-ray diffraction.When pH values of the extracts were adjusted to 10,the biosynthesized AgNPs were well-dispersed,highly stable,and relatively small in size.Thus obtained AgNPs were found to demonstrate good antibacterial activity against Escherichia coli and Staphylococcus aureus,with minimum inhibitory concentrations of 1.69 and 3.38 mg/L required,respectively.