气流式吹扫微注射器萃取技术在人参样品中五氯硝基苯及其代谢产物的GC/MS分析中的应用

Gas Purge Microsyringe Extraction for GC/MS Determination of Pentachloronitrobenzene,Pentachloroaniline and Pentachlorothioanisole from the Ginseng Complex Sample

为了快速而准确检测人参样品中的五氯硝基苯（PCNB）以及代谢产物五氯苯胺（PCA）和甲基五氯苯硫醚（PCTA）,建立了气体吹扫微注射器萃取技术与气相色谱-质谱（GC-MS）联用分析方法,实现了萃取和净化技术的一体化.本方法对PCNB、PCA、PCTA的平均加标回收率为79.6%-114%,相对标准偏差为4.6%-8.4%.与传统的索氏提取-浓硫酸净化方法比较,本方法具有快速、简便、重现性好等优点,可大大减少有机溶剂量和样品量,在中草药以及农作物的农残检测中具有良好的应用前景.

A gas purge microsyringe extraction（GP-MSE） for fast GC-MS determination of pentachloronitrobenzene（PCNB） and its metabolites pentachloroaniline（PCA）,pentachlorothioanisole（PCTA） in the ginseng was developed.It integrated extraction and clean up as one step.The average recovery of PCNB,PCA and PCTA in ginseng was 79.6%-114% and relative standard deviation was 4.6%-8.4%.Compared with Soxhelt extraction and concentrated sulfuric acid sulfonation-purification,this method is faster,simpler,has good reproducibility,and greatly reducing the amount of organic solvent and sample,while application of this method for measuring other herbs and pesticides residues in crops has a good prospects.