小儿咳嗽变异性哮喘与支原体感染关系研究

The relation of pediatric cough variant asthma and mycoplasma infection

目的:探讨小儿咳嗽变异性哮喘(CVA)与支原体感染关系。方法:通过选取本院2006年1月～2010年1月儿科门诊咳嗽变异性哮喘患儿108例为观察组,同期就诊、年龄相仿的上呼吸道感染的患儿100为对照组,使用间接血球凝集法测定方法对两组患儿的MP-IgM进行测定,观察组的MP-IgM(+)患儿使用大环内酯类进行治疗。结果:观察组108例患儿中MP-IgM(+)患儿46例,占42.59%,对照组MP-IgM(+)患儿11例,占11%。46例CVA合并MP-IgM(+)患儿在常规治疗基础上加用大环内酯类,总有效率为95%。对46例患儿进行为期7～24个月的随访,仅有2例患儿咳嗽轻度发作。结论:小儿咳嗽变异性哮喘与肺炎支原体感染有密切的关系,大环内酯类对此类患儿疗效显著。

Objective：To investigate the relation of pediatric cough variant asthma and mycoplasma infection.Methods：Selected 108 children with pediatric cough variant asthma from January 2006 to January 2010 as treatment group,choose the similar age and same period of the upper respiratory tract infection of children of the 100 as control group,detected the MP-IgM by using indirect hemagglutination blood determination method in two groups of children.Results：46 cases（42.59%） in treatment group were MP-IgM（＋）,11 cases（11%） in control group were MP-IgM（＋）.46 cases CVA with MP IgM（＋） in treatment group with conventional treatment combined with macrolides,the total effective rate was 95%.In 46 cases for a 7-24 months of follow-up,only 2 cases cough mild attacked.Conclusion：There is a close relation in pediatric cough variant asthma and mycoplasma pneumoniae infection,Macrolides,curative effect is distinct.