我院2007年至2010年老年尿路感染患者致病细菌及其耐药性研究调查

Our Hospital from 2007 to 2010 Elderly Patients with Urinary Tract Infection and Drug Resistance of Pathogenic Bacteria Investigation

目的了解我院2007年至2010年老年尿路感染患者致病细菌及其耐药性研究调查情况。方法对我院2007年至2009年的380例老年尿路感染患者取中段尿进行细菌培养。按照全国临床检验中心操作规程鉴定菌种,应用纸片扩散法进行药敏试验,按NCCLS标准判断结果。结果 380例患者尿细菌培养分离出400株细菌,主要为大肠埃希菌,男女感染率间差别有显著性意义(P<0.01)。其中以大肠埃希菌占多数,大肠埃希菌对阿米卡星、头孢由松、亚胺培南的耐药率较低,而对喹诺酮类、头孢噻肟、头袍哌酮、氨苄西林的耐药率较高。结论老年人尿路感染的致病菌主要为大肠埃希菌,男女感染率不同。常呈多重耐药性。抗菌药物的应用应当依据尿培养结果选择敏感药物,合理应用抗生素。

Objective Our hospital from 2007 to 2010 elderly patients with urinary tract infection and drug resistance of pathogenic bacteria in the investigation.Methods Our hospital in 2007 and 2009 380 cases of elderly patients with urinary tract infection urine for bacterial culture taken.Practice in accordance with national clinical laboratory,identification of strains,disk diffusion method for susceptibility testing,according to NCCLS criteria to judge the results.Results 380 cases of bacterial culture of urine of patients with isolated 400 bacteria,mainly Escherichia coli,differences between male and female infection rates are significant （P0.01）.The majority of which were Escherichia coli,Escherichia coli to amikacin,cephalosporins by the loose,imipenem resistance rates,while fluoroquinolones,cefotaxime,head gown piperazine ketone,ampicillin Higher resistance.Conclusion Urinary tract infection pathogens in the elderly mainly Escherichia coli,infection rates of men and women are different.Often has multiple drug resistance.The application of antimicrobial agents should be selected based on the results of urine culture sensitive drugs,rational use of antibiotics.