期刊文献+

阿德福韦酯治疗乙型肝炎肝硬化疗效分析 被引量:8

下载PDF
导出
摘要 目的观察阿德福韦酯治疗乙型肝炎肝硬化的疗效。方法 37例患者接受阿德福韦酯治疗,观察48周,另38例为对照。结果治疗组肝功能改善程度优于对照组;治疗组HBV DNA阴转率为84%,而对照组为2.6%(P<0.01);治疗组血清肝纤维化指标降低和门脉内径缩小程度均优于对照组。结论阿德福韦抗病毒治疗能明显改善乙型肝炎肝硬化患者的生活质量。
出处 《实用肝脏病杂志》 CAS 2011年第4期297-298,共2页 Journal of Practical Hepatology
  • 相关文献

参考文献10

二级参考文献12

  • 1曾民德,茅益民,姚光弼,周霞秋,王豪,徐道振,姚集鲁,侯金林,王宇明,任红,陈亚岗,牛俊奇,王耀宗.阿德福韦酯治疗HBeAg阳性的中国慢性乙型病毒性肝炎患者52周的多中心临床研究[J].中华传染病杂志,2005,23(6):387-394. 被引量:164
  • 2Minde Z,Yimin M,Guangbi Y et al.A double-blind randomized trial of adefovir dipivoxil in Chinese subjects with HBeAg-positive chronic hepatitis B.Hepatology,2006,108-116.
  • 3Hadziyannis SJ,Tassopoulos NC,Heathcote EJ,et al.Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B.N Engl J Med,2005,352:2673-2681.
  • 4Marcellin P,Chang TT,Lim SG,et al.Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B.N Engl J Med,2003,348:808-816.
  • 5Hadziyannis SJ,Tassopoulos NC,Heathcote EJ,et al.Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B.N Engl J Med,2003,348:800-807.
  • 6Peters M,Hann H,Martin P,et al.Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B.Gastroenterology,2004,126:91-101.
  • 7Perrillo R,Hann H,Mutimer D,et al.Adefovir dipivoxil added to ongloing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus.Gastroenterology,2004,126:81-90.
  • 8Hosaka T,Suzuki F,Suzuki Y,et al.Adefovir dipivoxil for treatment of breakthrough hepatitis caused by lamivudine-resistant mutants of hepatitis B virus.Intervirology.2004,47:362-369.
  • 9Jacob JR,Korba BE,Cote PJ,et al.Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model.Antiviral Res.2004,63:115-21.
  • 10Westland CE,Yang H,Delaney WE,et al,437 and 438 Study Teams.Week 48 resistance surveillance in two phase 3 clinical studies of adefovir dipivoxil for chronic hepatitis B.Hepatology.2003,38:96-103.

共引文献14042

同被引文献35

引证文献8

二级引证文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部