颈动脉硬化程度与冠心病的相关性分析

A research on relationship between carotid artery plaque and coronary heart disease

目的研究颈动脉内-中膜厚度(intima-media thickness,IMT)及颈动脉硬化斑块与冠心病(coro-nary heart disease,CHD)的发生之间关系。方法对205例可疑CHD研究对象行冠状动脉造影,根据造影结果分成CHD组和非CHD组;再对两组研究对象做颈动脉超声检查,测量颈动脉IMT,分析颈动脉硬化斑块与冠心病发生的相关性。结果非CHD组64例,CHD组141例,IMT分别为(0.75±0.11)mm和(1.06±0.23)mm;颈动脉斑块的发生率分别为23.43%(15/64)和78.01%(110/141)。两组比较差异有统计学意义(P<0.01)。结论颈动脉内一中膜厚度(IMT≥0.90 mm)或出现颈动脉硬化斑块与冠心病的发生具有高度相关性。颈动脉粥样硬化是冠心病的高危因素,颈动脉超声检查可作为筛选冠心病的指标。

【Objective】 To study the relationship between carotid intima-media thickness（IMT）,carotid artery plaque and coronary heart disease.【Methods】 205 cases suspected with coronary heart disease（CHD） were divided into non-CHD group and CHD group according to coronary angiography result,also they were examined by carotid artery ultrasound examination,the IMT was measured and the relationship between carotid artery plaque and coronary heart disease was observed.【Results】 There were 64 cases without CHD and 141 cases with CHD.The IMT significantly increased in CHD group [（1.06±0.23）mm vs.（0.75±0.11）mm,P〈0.01].The prevanlence rate of atherosclerotic plaques in CHD group[78.01%（110/141）] was significantly higher than that in non-CHD group [23.43%（15/64）,P〈0.01].【Conclusion】 The carotid IMT and atherosclerotic plaque have close relationship with coronary heart disease.Carotid artery ultrasonography has great value for predicting CHD.