有机酸复方消毒剂杀灭微生物作用与毒性的实验观察

EXPERIMENTAL OBSERVATION ON GERMICIDAL EFFICACY AND TOXICITY OF COMPOUND DISINFECTANT OF ORGANIC ACIDS

以含多种有机酸的复方消毒剂０ ．５０ ％ 溶液，对金黄色葡萄球菌作用１０ ｍｉｎ，对白色念珠菌作用１５ｍｉｎ ，杀灭率均达１００ ％ 。在试验范围内，其杀菌效果随温度升高而增强，受有机物影响不明显。该剂存放于５４ ℃较稳定，属低毒类，２ ．０ ％ 溶液对皮肤无刺激。

Thecompound disinfectantoforganicacidsiscomposed oforganicacidssuch as benzoic acid, lactic acid and salicylic acid.The average killing rate ofboth Staphylococcusaureusexposedtoits 0 .25 % solution for10 min and Canidida albicans exposed toits 0.50 % solution for 5 min was over 99 .9 % .The killing rateof S.aureusexposedtoits0 .50 % solutionfor10 min and Candi da albicansexposed for 15 min attained 100 % . Within the range oftemperaturetested,the ger micidalefficacy ofthis disinfectantincreased with increasing temperature,butits efficacy was not influenced obviously by organicsubstances.Its germicidalefficacy did not decrease obviously after storing at 54 ～56℃for 14 days.Its 2 .0 % solution had noirritative effect on the skin ofrabbit andits LD50ofintragastric administrationin mice was 4755 mg/kg,soit belongsto substances of low toxicity.