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氨磷汀预防顺铂化疗的血液毒性和肾毒性疗效观察 被引量:8

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摘要 目的观察氨磷汀预防顺铂血液毒性和肾毒性的临床疗效及其安全性。方法将60例非小细胞肺癌患者随机分为化疗+氨磷汀组(观察组)、单纯化疗组(对照组)各30例,于化疗前后检测其血象、血清肌酐、肌酐清除率、尿素氮、尿β2-微球蛋白和尿白蛋白。结果化疗后,观察组血液毒性和肾毒性明显低于对照组(P<0.05)。结论氨磷汀能明显减轻顺铂化疗方案引起的血液毒性和肾毒性。
机构地区 滨州市人民医院
出处 《山东医药》 CAS 北大核心 2011年第25期90-91,共2页 Shandong Medical Journal
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参考文献4

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二级参考文献31

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